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You Can Move, But You Can’t Hide
… to replicate themselves and spread from cell to cell. Two of the most common forms of MGEs are viruses and plasmids. They can be found in … software tool  recently described in  Nature Biotechnology  called geNomad identifies and classifies MGEs based upon … Exascale Computing Project (17-SC-20-SC), a collaborative effort of the U.S. Department of Energy Office of Science and …
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Engagement Webinar: Utilizing long-read sequencing for metagenomics and DNA modification detection
… to aid with genome assembly and transcriptome analysis of microbial, fungal, and plant research projects.  More … Input & sequencing Q(uestion): How much DNA is needed for “regular” vs the ultra-low input library creation … protocols for PacBio? A(nswer):  Regular PacBio typically requires ~ 1.5-10 ㎍. Low-input protocols are …
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Honey Bee Gut Microbiota Divvy Up Dinner
… Scientists find bee gut microbes have a division of labor when it comes to metabolizing complex … in the next generation of flowering vegetation. In return for their services, bees eat plant nectar and pollen. Nectar … which have complex, branching chains of polysaccharides called pectin and hemicellulose. While these two …
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Sequence to Function: Applications and Analysis for the Future (SFA²F)
… The Sequence to Function: Applications and Analysis for the Future (SFA²F) meeting brings together established … from academia, industry, and government organizations for three days of scientific presentation, interactive panel discussions, …
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Discovery and ecogenomic context of a global Caldiserica-related phylum active in thawing permafrost, Candidatus Cryosericota phylum nov., Ca. Cryosericia class nov., Ca. Cryosericales ord. nov., Ca. Cryosericaceae fam. nov., comprising the four species
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Expanding Virophage Diversity
… in  Microbiome , researchers from the US Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office … & Microbiomes (IMG/M) data suite—which includes  IMG/VR (for Virus)—for the virophage marker gene MCP, they were able … even animal and human (for the first time) gut and taxonomically classified into 27 distinct clades (17 of them without …
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Building Wet and Dry Lab Skills
… Summer 2025 marked the second year of Alabama A&M University students coming to the DOE Joint Genome Institute for research and training experience funded by a DOE … out the biome of. Tamyra Long : The other side is what we call the dry lab. We've been focused on analyzing plant …
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Designer DNA: JGI Helps Users Blaze New Biosynthetic Pathways
… A special issue of Synthetic Biology celebrates research enabled by the JGI … a special class of compounds, or secondary metabolites, called terpenes. Terpenes are made via a tangled network of … PI on this project. “I view the program as an excellent platform to build collaborative research initiatives.” Yasuo …
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A Plant Root Atlas for Tracking Developmental Trajectories
… A collaborative team led by Geoffrey Schiebinger at the University of British Columbia, … nearly 100,000 single root cells and combining the information with previously published datasets. The work was  … in 2017. In 2019, plant single-cell methods were officially called out as one of four program development areas for one …
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The Genome of the Acid Soil-Adapted Strain Rhizobium favelukesii OR191 Encodes Determinants for Effective Symbiotic Interaction With Both an Inverted Repeat Lacking Clade and a Phaseoloid Legume Host
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JGI Early Career Researchers Featured in mSystems Special Issue
… In a special issue of mSystems , out May 14, 2019, JGI researchers are among … sorting (FACS) to sort cells into several small pools before sequencing to recover rare microbes. The technique was … probing (DNA SIP) relies on incubating DNA with isotopically-labeled compounds to link active microbes with …
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Finding the Fermenters
… researchers built an interactive and comprehensive database of fermentative prokaryotes. The Science Most organisms use … had found other ways to produce energy, using a process called fermentation. To better understand the range of bacteria and archaea that rely on this form of metabolism, researchers recently compiled a list of …
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