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Deletion of either the regulatory gene ara1 or metabolic gene xki1 in Trichoderma reesei leads to increased CAZyme gene expression on crude plant biomass
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Global distribution of a wild alga revealed by targeted metagenomics
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Targeted diversity generation by intraterrestrial archaea and archaeal viruses
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Precision Drug Targeting: Understanding the Intracellular Transport Mechanism
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Targeted hypermutation of putative antigen sensors in multicellular bacteria
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Genome sequencing of Rigidoporus microporus provides insights on genes important for wood decay, latex tolerance and interspecific fungal interactions
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Sequence to Function: Applications and Analysis for the Future (SFA²F)
… The Sequence to Function: Applications and Analysis for the Future (SFA²F) meeting brings together established and emerging scientists from …
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Designer DNA: JGI Helps Users Blaze New Biosynthetic Pathways
… Fashioning DNA outside a cell is key to interrogating what genes do, how they work, and applying them to environmental … of DNA constructs encoding a molecular tool to repress targeted genes in the organism. The team demonstrated that … and her own as an early career researcher. “We were able to study hydrocarbon biosynthesis at a scale that would …
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An Enzyme Family that Helped Shape Nitrogen Metabolism on Our Planet
… to the way many organisms function, they have a sense of why nitrogen metabolisms can be so varied.  As evolution has … around, regardless of malfunction or misplacement.  In studying this family of ATs, researchers found that these … This analysis led them to identify 2,938 putative AT  genes. Within the AT genes identified across different …
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Ian Blaby
… Since 2019 Dr. Blaby heads the Biodesign Platform at the Joint Genome Institute, where he leads three groups focused on … with a view to developing a deeper understanding of sequence-based gene function. … B.Sc. (HONS) – University of Wales, Cardiff, Genetics Ph.D. – University of Cambridge., Microbial …
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Model Fern Reveals Insight into DNA Thievery in Ferns
… event that occured some 60 million years ago. Massive gene loss, rampant gene duplications, and even more ancient … power of plants, and the lessons they can teach us, are why the U.S. Department of Energy (DOE) Joint Genome … richardii marks the first published manuscript of a genome sequence generated through the OGG. For a long time, C-fern …
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An Addiction Crucial to a Fungus’ Reproduction
… organisms (symbionts) are transmitted between host generations, researchers investigated the role that bacteria … with the fungi and bacteria, while the DOE JGI team sequenced and annotated a host genome (Rm ATCC 52813) as … reliant on the continued presence of the bacteria. By studying the Rm-Burkholderia symbiosis model, the team was …
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