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An Enzyme Family that Helped Shape Nitrogen Metabolism on Our Planet
To boost crops more efficiently in the future, the evolutionary past may hold key insights. The way that plants process nutrients has a rich back story — they rely on … processes both carbon and nitrogen. This research team combined computational and experimental approaches to look …
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Crysten Blaby-Haas
University of Florida, working with Valérie de Crécy-Lagard on using comparative genomics to predict gene function in bacteria … hypotheses. From 2011 – 2015, she worked with Sabeeha Merchant at UCLA as a NIH Ruth L. Kirschstein National Research …
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Enlarging Windows into Understanding Gene Functions
JGI innovates protocol revealing how genetic variations in sequences affect traits. In a text file, the rows of … T, C and G appearing over and over in a dizzying array of combinations, are unremarkable, save perhaps for the absence … species to answer questions about how they break down plant materials, which could be useful for industrial biofuel …
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Micro-Scale Applications Group
The Micro-Scale Applications group explores the genetic makeup of natural microbial communities using a variety of cutting-edge approaches.  Our … Research Team    … The JGI uniquely offers the first quantitative Stable Isotope Probing (SIP) Metagenomics …
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DOE Metrics
FY 2025 DOE Metrics Sequencing Quarter Total Bases (Trillions) Operating Hours Goal Actual Total* Actual % of Goal … Goal = 91 days; Actual Operation = 24 days due to significant sequencer downtime related to the shelter-in-place. ††† … hours. Other DOE Quarterly Metrics Q1 – Report on new computational developments for improving microbial, …
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Synthesis
Platform capabilities support researchers exploring how to convert sequence into functional assessments. This is done by synthesizing genes, … to automate sequence design for assembly by Gibson, Yeast recombination and Golden Gate methods … gRNA-SeqRET … BOOST … …
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Researching and Solving Real-World Problems with the 2023 JGI-UC Merced Interns
Program was brimming with excitement and determination as they came onsite. From data carpentry to science communications, their schedules were filled with trainings … Study of Root Colonization by Resident Phages of a Plant Growth Promoting Rhizobacterium Graduate Interns Tahirah …
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Taking Stock of the Known and Unknown Microbial Space
… have led to an abundance of microbial genomes becoming available to the global research community.  … of Science User Facility located at Lawrence Berkeley National Laboratory Berkeley Lab), have taken stock of the … Ivanova leads the Functional Annotation team. MAGs significantly expanded the estimated diversity of Bacteria and …
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A Complex Confection Decoded: Sugarcane Reference Genome
… work toward advancing sugarcane biotechnology. The Science Considered the world’s most harvested crop by tonnage, … other crops facing similar pathogens. Summary Many plants, sugarcane included, are polyploid and have multiple … 80% of sugar production worldwide, but has one of the most complex genetic blueprints. Assembling a genome has been …
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Notes on the Microbial Diversity of Puerto Nuevo’s Coastline
Puerto Nuevo is a small town along the Baja California coastline in Mexico. While … California-Baja coast and spots where they are most abundant are Monterey, San Diego, and Puerto Nuevo.” Ul-Hasan’s … I have today. I didn’t know anything about Principal Component Analysis (PCAs) when I first started, and overall …
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Plant-Microbial Interactions Group
Plants are complex organisms that harbor a fantastic diversity of cell types and associated organisms, including fungal and bacterial symbionts, detrimental microbial pathogens, and associated …
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Hiroshi Otani
Genome Institute in 2016, Dr. Otani has been studying secondary metabolism in microbes, particularly actinomycetes. His research activity is focused on developing and implementing new technologies and … 2023 Feb 17;50(1):kuad005.  Otani H, Udwary DW, Mouncey NJ. Comparative and pangenomic analysis of the genus …
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