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Extracting the Secrets of Secondary Metabolites
… now be easier to characterize following a proof-of-concept study in which researchers paired CRISPR and CRAGE … vital products in biotechnology, medicine, agriculture, and other industries — yet there’s still so much about them we … of interest. Using CRAGE to domesticate target microbes, users of the U.S. Department of Energy (DOE) Joint Genome …
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Plotting a Model for Virus-Host Warfare Deep Below Ground
… below the Earth’s surface is reconstructed by combining a study of microbial communities (metagenomics) and a chemical … fresh organic carbon which can serve as a food source for other microbes into the environment. Summary In J. R. R. … (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at Lawrence Berkeley National …
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Viruses Reprogram Cells into Different Virocells
Microbial cells infected by viruses undergo metabolic reprogramming. The Science If it looks like a duck and quacks … The Ohio State University and the University of Michigan studying how virus infections cause significant metabolic … in part by the  Facilities Integrating Collaborations for User Science (FICUS) collaborative science initiative …
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From Berkeley to Binghamton: Tracking Strawberry Evolution
… method can be  accessed here so that, Session said, other scientists can “follow a step-by-step process to apply … every single gene from octoploid strawberry, compared it to other non-polyploid strawberries, and said ‘whichever gene … These days, Session is starting his lab at Binghamton “studying polyploids and transposon evolution, expanding on …
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An Age of CRAGE: Advances in Rapidly Engineering Non-model Bacteria
… is central to our ability to offer host-engineering for our users,” says JGI Director Nigel Mouncey. Using CRAGE, JGI … Opinion in Biotechnology . Now, CRAGE is being applied to other synthetic biology problems. For example, a group of … group of bacterial strains as part of the Community Science Program (CSP)  Functional Genomics proposal call. …
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Cas9-Based Metabolic Engineering of Issatchenkia orientalis for Enhanced Utilization of Cellulosic Hydrolysates
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A New Actinobacterial Chapter in the Genomic Encyclopedia of Bacteria and Archaea
… (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at Lawrence Berkeley National … (Berkeley Lab), to fill in these gaps of knowledge. In a study published November 11, 2022, in Cell Genomics , the … to environmental stresses or mediate interactions with each other (sometimes antagonistic ones, via antimicrobials) – …
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JGI Contributes Eight to 2023 Highly Cited Researchers list
Catalog . Published in the October issue of Nature, the study highlights the vast functional diversity of microbes … sequences. Roux was first author on a study featuring a new program called iPHoP , which combines and evaluates multiple … and found that, while they often act as parasites, others actually help their hosts. …
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Giant Bacteria Found in Guadeloupe Mangroves Challenge Traditional Concepts
… it into context, it would be like a human encountering another human as tall as Mount Everest,” said Jean-Marie … (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at Lawrence Berkeley National … sediments,” said Woyke, who also heads the JGI’s Microbial Program and is one of the article’s senior authors. The team …
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Evolution of a Fungal Gene Expression Regulator
… in transposable elements or transposons that can move to another location in the genome. Many plant pathogens such as … (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility, and others like it, are uncovering the true … of Energy Joint Genome Institute, a DOE Office of Science User Facility, is supported by the Office of Science of the …
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New Research Finds Flagella in the Terrestrial Roots of Marine Bacteria
Ancient  Chloroflexota s ditched their flagella and other traits when migrating back to the ocean. The Science … chemicals not typically found in oceans or soils.  A recent study published in  The ISME Journal     focused on a class … of Energy Joint Genome Institute, a DOE Office of Science User Facility at Lawrence Berkeley National Laboratory, has …
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Doubling Down on Known Protein Families
… — worse, they didn’t even know how big the room is.  A new study  published online Oct. 11, 2023 in  Nature highlights … (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at Lawrence Berkeley National … (Berkeley Lab), and collaborators across multiple other research centers around the world. “We’ve more than …
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