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Boosting Small Molecule Production in Super “Soup”
… the small molecules glycerol and itaconic acid to see how the cell-free system allowed them to increase the … in the absence of cell walls. If we can continue to learn how to focus the carbon flux, we can avoid transport …
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Mining Public Databases Yields Largest Map of Fungal Mitochondrial Genomes to Date
… dataset of its kind ever assembled. The team identified 15 core genes shared across all fungi, and found that some of … dataset gives researchers a new foundation for studying how fungi produce and manage energy at the cellular level. … trees built from mitochondrial and nuclear genomes showed strong agreement across the kingdom, confirming that …
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Mining Metagenomes for Cas Proteins
… disease. Finally, gene editing is being used to understand how a person’s genetic makeup predisposes them to, or … previously known class 2 CRISPR enzymes that are typically 950—1400 aa. They were initially identified by searching for … and Nanohaloarchaea. This work represents an excellent showcase of the unique capabilities provided from the IMG/M …
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An Age of CRAGE: Advances in Rapidly Engineering Non-model Bacteria
… users will enable us to assess CRAGE’s impact, including how this application could scale,” says Mouncey. The JGI …
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Finding the Fermenters
… Most organisms use oxygen to convert food into energy. However, in environments with little or no oxygen, life had … of these microbes. The Impact This study illustrates how the research community brings together the data … interactive browser – contains the phenotypic records of 8,350 organisms along with 4,355 genomes and 13.6 million …
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Polar Phytoplankton Need Zinc to Cope with the Cold
… function and activity of phytoplankton genes and looking at how communities of these microalgae interact, researchers … analysis as well as laboratory culture experiments showed that those zinc-binding proteins are important for … data from the JGI. With multiple threads of evidence showing that zinc has allowed polar algae to inhabit their …
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Evolution of a Fungal Gene Expression Regulator
… the largest analysis to date of the modified DNA base 5mC variations in fungi. The Science Changing an A, C, T or … DNA base is a methylation of the base cytosine at the 5th position on its carbon ring, or 5mC. In many organisms, 5mC is an important piece of how they regulate their genomes, but is not well understood …
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Introducing New Members of the JGI User Executive Committee
… but use-restricted] exist on [the JGI data portal] IMG or how to deal with situations in which they inadvertently …
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JGI@25: The Little Alga That Could
… In honor of the JGI's 25th anniversary in 2022, we have revisited a number of notable achievements that showcase our collaborations and capabilities to enable great … of C. reinhardtii became available, data mined by the JGI shows that those sequences have been cited in almost …
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Boosting Small Molecule Production in Super “Soup”
… the small molecules glycerol and itaconic acid to see how the cell-free system allowed them to increase the … in the absence of cell walls. If we can continue to learn how to focus the carbon flux, we can avoid transport …
Learn more
Innovative Technology Improves Our Understanding of Bacterial Cell Signaling
… Newly developed chemiluminescent biosensors shed light on how bacteria function and colonize diverse environments. The … the U.S. Department of Energy under Contract No. DE-AC02-05CH11231. This work was supported in part by NIH grants DP2 OD008677 and R01 GM124589, NIH training grant T32 GM066698, and UC Berkeley …
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Alabama A&M Interns Access An Abundance of Knowledge
… CRISPR Cas9 knockout mutants to observe and investigate how transporter proteins regulate the production of root …
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