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Toward More Reproducible, Reusable Stable Isotope Probing Experiments
As SIP experiments shed more light on microbial communities than ever before — especially with … work to create FAIR datasets to maximize returns on these advances. Over the last two decades, Stable Isotope … of stable, heavy isotopes, SIP allows researchers to go beyond understanding which microbes are present in a sample, to …
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Taking Stock of the Known and Unknown Microbial Space
… of Science User Facility located at Lawrence Berkeley National Laboratory Berkeley Lab), have taken stock of the … the past three decades, their study assesses what fraction of the microbial diversity we know about, and proposes a … is still unknown.  “We took a deep dive into over 1.8 million bacterial and archaeal genomes to see how much of their …
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How to Target a Microbial Needle within a Community Haystack
… make-up of specific uncultivated microbes from complex environmental samples. The Science A team led by researchers at … targeted genomic approach would allow researchers to focus on specific microbes within metagenome samples and associate … their sequences with their roles within their environments. Summary The traditional shotgun metagenomics …
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Toward More Efficient Artificial Photosynthesis
Chloroplast mimic a platform to capture and utilize carbon in a synthetic fixation cycle. The Science Chloroplasts are the factories in … they take raw materials including sunlight, carbon and water, to convert them into energy that is then …
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The More the Merrier: Making the Case for Plant Pan-genomes
Brachypodium model system traces polyploid genome evolution. Flowering plants abide by the concept, “the more the merrier,” with respect to their … their base state, they are diploids with two genome copies, one from each parent. Having three or more genome copies …
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Extracting the Secrets of Secondary Metabolites
… biosynthetic gene clusters.  The Science Microbial secondary metabolites, those molecules not essential for growth … may now be easier to characterize following a proof-of-concept study in which researchers paired CRISPR and CRAGE … with CRISPR provides researchers with a powerful addition to their toolkit to study gene function. As a …
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When “The Blob” Made It Hotter Under the Water
… marine heatwave event may foreshadow climate change impact on marine microbial communities. The Science A team of … ocean known as “The Blob.” The event was recorded during a long-term study of microbial communities in the northeastern … in the ocean drive the biological pump that takes carbon from the atmosphere and keeps it in the deep ocean. With …
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The Expanding Universe of Methane Metabolisms in Archaea
Methane is a greenhouse gas 20 times more potent than carbon dioxide. Billions of years ago, methane-producing archaea likely played a key role in determining the composition of the Earth’s atmosphere and regulating the global …
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JGI Workshop at SIMB NP Meeting
Jan. 7: New Capabilities to Study Secondary Metabolism   Although there are still a large number of secondary metabolites yet to be discovered and their … intensive. This is often due to, for example, tight regulation of biosynthetic gene clusters (BGCs) in native hosts, the …
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JGI Early Career Researchers Featured in mSystems Special Issue
… issue of mSystems , out May 14, 2019, JGI researchers are among the authors who offer perspectives on what the next five years of innovation could look like. In one article, Micro-Scale Applications …
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Honey Bee Gut Microbiota Divvy Up Dinner
Scientists find bee gut microbes have a division of labor when it comes to metabolizing complex polysaccharides. Honey bees are invaluable pollinators — cupids of the plant … facilitating the remixing of genes in the next generation of flowering vegetation. In return for their services, …
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In Hot Spring Microbial Mat, Viruses Ride “Piggyback”
In microbial mats, communities of microorganisms live among viruses that infect them. But what trends govern those virus-host interactions? Do generalist viruses run rampant, capable of infecting … that they lyse the cell — a process called lytic infection. But some viruses are also able to play a long game. In a …
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