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Boosting Small Molecule Production in Super “Soup”
… (Spoiler: Yes.) Think of cells as tiny factories: within their walls they have both the machinery to make … cell)and in vitro (outside the cell) efforts of this work when it started. Though such visits have been impossible for … can be enabled by this technology, but also what we can understand through this technology.” “This is a fantastic …
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Taking Stock of the Known and Unknown Microbial Space
… Metagenomic datasets could help map out microbial diversity hotspots Over the past few decades, advancements in … global nutrient cycles. The information gained from understanding the interactions between microbes, hosts, and … 36% of archaeal diversity with no genomic representation. “When it comes to isolate genome data, our real-world …
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Doubling Down on Known Protein Families
… computational approach, researchers confirm microbial diversity is wilder than ever. Imagine researchers exploring a … to clearly identify what falls within that single beam. When it comes to microbial communities, scientists have … diversity of microbes through a novel approach to better understand microbial communities by looking at protein …
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A Better Way to Find RNA Virus Needles in the Proverbial Database Haystacks
… book featuring polar bears in winter scenes that came with crayons in various shades of white. To researchers searching for sequences of RNA viruses … every virus carries, and who is their likely host. We’ve made all of that information fully free and openly available …
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Mission
… As a U.S. Department of Energy Office of Science user facility, we provide advanced genomic capabilities, large-scale AI-ready data and professional expertise to support the global research community in studies of complex biological and environmental … resource resilience and economic growth. The DOE, through its BER program, plays a central role in advancing this …
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Tracking the Origins of Methane-Producing Microbes
… Academy of Sciences , researchers at Stanford University, the Chan Zuckerberg Biohub, and the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science user facility, report … evolutionarily from other previously discovered genomes. When they analyzed the reconstructed metabolisms, they found …
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JGI Contributes Eight to 2023 Highly Cited Researchers list
… Congratulations to the 2023 Highly Cited Researchers from the JGI recognized for their … field or fields through the publication of multiple highly cited papers during the last decade” by Clarivate Analytics. … lignin , the hardiest of plant components and a key barrier when breaking down biomass. He was also senior author on a …
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Boosting Small Molecule Production in Super “Soup”
… conversion of glucose to value-added products are limited in chemical output due to growth and viability … cell)and  in vitro  (outside the cell) efforts of this work when it started. Though such visits have been impossible for … can be enabled by this technology, but also what we can understand through this technology.” “This is a fantastic …
Learn more
Webinar: PhycoCosm Tutorial
… need to be changed, please contact us and we’ll work work it out 2.  Q(uestion): Do you publish the data sets the … We do plan to publish the tree or their parts and data it is based on 3.  Q(uestion): Can you please explain again … we provide full analysis (assemble, annotate, work on initial analysis) and share data in PhycoCosm. For genomes not …
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Webinar: SIP technologies at EMSL and JGI
… Sciences Laboratory (EMSL) and the Joint Genome Institute (JGI) provide access to a variety of tools that … EMSL such as DNA-SIP, Protein SIP, Flux Balance analysis with metabolites, Isotope Ratio Mass Spectrometry, NanoSIMS, and other … The U.S. Department of Energy Joint Genome Institute, a DOE Office of Science User Facility  located at …
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Expanding Horizons with the 2025 JGI-UC Merced Internship Cohort
… at the U.S. Department of Energy (DOE) Joint Genome Institute, a DOE Office of Science User Facility. This year, the 12th JGI-UC Merced cohort consisted of three undergraduate students and eight graduate students, hosted … research projects through the DOE RENEW grant initiative when school starts in the fall.  Outside of the technical …
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The Expanding Universe of Methane Metabolisms in Archaea
… archaea likely played a key role in determining the composition of the Earth’s atmosphere and regulating the global … For Guillaume Borrel and Simonetta Gribaldo of the Institut Pasteur in France, the importance of methanogenesis and … suggest the diversity of methane metabolisms is “vastly underestimated.” In the March 4, 2019, issue of Nature …
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