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… gas, regulate Earth’s climate. Most methane is produced in environments without oxygen through a process called … bioeconomy, including, potentially, methane as an energy source.  Until recently, our understanding of these … shows methanogenesis is not limited to  Euryarchaeota .  Finding Methane-Making Microbes with Metagenomics  By …

Fine-tuning metabolic gene expression helps identify variants … available for other JGI users outside the realm of bioenergy optimization. Summary Life is all about balance. This … Alper’s team discovered new gene targets to more efficiently grow on these sugars. To demonstrate the …

… can in turn boost yields for both food and for candidate bioenergy feedstock crops. Summary A plant is like an office … Lawrence Berkeley National Laboratory (Berkeley Lab). Their findings were described in a recent Nature Communications … from ancestors that were likely harmful to plants and can efficiently colonize roots by degrading the plant cell wall …

… with the prospect of meta-analyses boosted by AI and Machine Learning — JGI researchers and collaborators work to … as a capability in proposal calls to the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of … these experiments create data aligned with FAIR principles (Findability, Accessibility, Interoperability, and …

… are small viruses with double-stranded DNA genomes that co-infect eukaryotic cells along with giant viruses. Virophages … in  Microbiome , researchers from the US Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of … Symposium. The work also used resources of the National Energy Research Scientific Computing Center (NERSC) , which …

… enabled by the JGI DNA Synthesis Science Program. Fashioning DNA outside a cell is key to interrogating what genes … do, how they work, and applying them to environmental and energy challenges. But not all scientists have the expertise … and synthesis work. This is where the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of …

… uncultivated bacteria offers clues to ancestral bacteria’s energy sources. More than two billion years ago, … development of multicellular organisms. Not all bacterial lineages harnessed aerobic respiration when the Cyanobacteria … strategies other than photosynthesis to gain and harness energy. As reported January 28, 2019 in Nature …

Do metabolic pathways from engineered yeasts still work in cell-free environments? … Technologies Opportunity Program at the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of … scales. “Cell-free systems have been really powerful at finding ways to accelerate bio-design and identifying the …

A deep dive into microbial genomics reveals one bacterial species is … Tanja Woyke and Rex Malmstrom at the U.S. Department of Energy Joint Genome Institute (JGI), a DOE Office of Science … life; they can fix carbon dioxide, but they drive that high-energy reaction using simple inorganic sulfur-containing …

Machine learning approach significantly expands inovirus … , a team led by scientists at the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of … San Francisco. Both are co-authors on the study. “By finding a new anti-CRISPR locus, in an inovirus for example, …

Phytozome workshop held during the June 2022 CROPS Conference at the HudsonAlpha Institute for Biotechnology. Phytozome is the Plant Comparative Genomics portal of the Department of Energy Joint Genome Institute, and facilitates accurate and …

In honor of the JGI's 25th anniversary in 2022, we have … capabilities to enable great science that will help solve energy and environmental challenges. Congratulations to … analyses to continuously refine and improve the process of finding novel Cas genes and CRISPR systems. The …