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Refining the Process of Identifying Algae Biotechnology Candidates
… well ] The Science The recipe for growing algae as a source of sustainable biofuels seems fairly simple: place these … the right ingredients. Researchers collaborating across multiple institutions have sequenced and analyzed the genome … date of any such strain, identified through a screening and characterization pipeline. The Impact Part of the Department …
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Transcriptional control of Clostridium autoethanogenum using CRISPRi
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UC Merced Interns Reflect on Their JGI Summer Projects
Over the course of eight weeks this past summer, 10 students from UC Merced … on research projects that contribute to the larger mission of the U.S. Department of Energy. Students also worked with … summer. The JGI-UC Merced internship program was founded in 2014 with the goal of inspiring students to embark on a …
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CSP Functional Genomics
Genomics call is to enable users to perform state-of-the-art functional genomics research and to help them … synthesis and ‘omics capabilities to enhance understanding of gene and genome function, particularly those not readily … and analysis will be paid for by the Department of Energy’s funding of the JGI. There is no cost to the user …
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Frederik Schulz
Genome Institute in 2016 and is leading the New Lineages of Life Group. His research is focussed on the discovery of … multi-omics (metagenomics, metatranscriptomics, single cell genomics and phylogenomics) and machine learning to … academic achievements (2008) … Education … Selected Publications … Awards and Service …
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Biochemical characterization of Fsa16295Glu from “Fervidibacter sacchari,” the first hyperthermophilic GH50 with β-1,3-endoglucanase activity and founding member of the subfamily GH50_3
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JGI@25: Expanding Metagenomics to Capture Viral Diversity
In honor of the JGI's 25th anniversary in 2022, we have revisited a … are everywhere — in soil, the sea and, of course, the cells of other organisms. As they infect microbes like … over 125,000 partial and complete viral genomes. That study multiplied the number of known viral genes by a factor of …
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A Revamped Amplification Method that Enables Nearly Complete Single-Cell Genomes
… are now getting more complete genomic results from single cells. The Science Studying the  genomes of microorganisms is incredibly useful for understanding the … way of collecting them is through a method called Multiple Displacement Amplification, and most genomes that …
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A Community Resource for Secondary Metabolite Researchers
… user engagement. The Science In addition to the core set of "primary metabolites"—chemical compounds shared by most … more than 13 million BGCs in the catalog at the time of publication, it is the largest repository of BGC sequence … repository of BGC sequences that come pre-annotated using multiple commonly used sequence analysis tools is a means of …
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2025 NeLLi Symposium
Hosted by the DOE Joint Genome Institute, the University of Nevada, Las Vegas, and the Desert Research Institute, the … Tree of Life and latest discoveries toward the evolution of cellular complexity and microbial symbiosis.  This is a … the extent of diversity. The phylogenetic and functional characterization of this novel diversity represents an …
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Kanwar Singh
Kanwar spends part of his time assisting JGI users by processing their single cell samples using our high throughput pipeline. He also …
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Streamlining Regulon Identification in Bacteria
… with their target genes. The Science Regulons are a group of genes that can be turned on or off by the same regulatory … transcription-sequencing (RIViT-seq) to facilitate the characterization of transcriptional regulation as well as … sets associated with functions like stress responses and cellular differentiation. The tough part is identifying the …
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