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Leo Baumgart
… his doctoral research in synthetic biology and microfluidics at the University of California, San Diego. As the Sequencing Technology … a method that enables high-throughput characterization of transcription factor binding sites and which has been … BS in Biochemistry and Cell Biology, University of California, San Diego PhD in Molecular Biology, …
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Better Genome Editing for Bioenergy
… A team has optimized a crucial part of CRISPR-Cas9 technology to enable improvements in … Cas9 needs guide RNA to lead it to the correct sequence to snip — but not all guides are effective. To … sgRNA sequences: six for every gene in the genome. The JGI  DNA Synthesis Science team synthesized these sgRNAs, cloning …
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Ecogenomics reveals community interactions in a long-term methanogenic bioreactor and a rapid switch to sulfate-reducing conditions
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Discovery of Novel Plant Interaction Determinants from the Genomes of 163 Root Nodule Bacteria
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Ecosystem Fabrication (EcoFAB) Protocols for The Construction of Laboratory Ecosystems Designed to Study Plant-microbe Interactions
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QTL × environment interactions underlie adaptive divergence in switchgrass across a large latitudinal gradient
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Viruses interact with hosts that span distantly related microbial domains in dense hydrothermal mats
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Short sequence motifs, overrepresented in mammalian conserved non-coding sequences
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JGI@25: Strengthening Soybean
… In honor of the JGI's 25th anniversary in 2022, we have revisited a … first legume species with a published complete draft genome sequence. At the time, the vital global source of both … guys,” said Duplessis, who has collaborated with the JGI on multiple projects involving rust pathogens. “All along the …
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Evolution of a Fungal Gene Expression Regulator
… Describing the largest analysis to date of the modified DNA base 5mC variations in fungi. The Science Changing an A, C, T or G in a genome sequence can lead to changes in protein structures and … The work conducted by the US Department of Energy Joint Genome Institute, a DOE Office of Science …
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Fields of Breeders’ Dreams: A Team Effort Toward Targeted Crop Improvements
… crop and ornamental seeds sold for the upper Midwest are often very different than those bred for Texas. Identifying … (Berkeley Lab), has produced a high-quality reference sequence of the complex switchgrass  genome using samples … of clonally propagated plants to address these questions.” Multiple collection methods were applied to gather the …
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From Intern to Published Scientist: The Journey of a JGI-UC Merced Intern
… For many scientists, the culmination of their work into a written report that is published in a … current PhD student, reached this milestone with a recent publication in Molecular Biology and Evolution . “It’s my … applications, Wint also developed and tested a gene sequence-based predictor of gene expression levels using …
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