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… Repeats) is the leading tool for accurately editing genomes, its effectiveness has historically been limited due to the lack of robust tools available for carrying CRISPR into microorganisms. … monitor loss- and gain-of-function. The study’s analytical data shows peaks and valleys in secondary metabolites as …

… that can’t be cultured by analyzing and then extrapolating data obtained from environmental samples — to identify over … coherent pieces called contigs — into genes and even into genomes — from these environmental samples,” said Matthias … and … that was really the foundation for many of the tools that are available these days and that are widely used …

… (OLCF), NVIDIA, and the Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science user … is one of the largest producers of environmental genomics data and has a strong reputation in the community,” said JGI … Officer Kjiersten Fagnan of the upcoming event. “The tools we use to process and analyze these data are diverse …

… scientist at the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User … or DRI for short.  A kaleidoscope of structure-function data To study DRI experimentally, Blaby-Haas, Grosjean and … Scientists at Stanford’s SSRL were able to provide crucial data supporting the presence of the zinc-mirror heme site — …

… mobile genetic elements that were missed within paired metagenome assembled genomes (MAGs), and that dominant … advances in sequencing technologies and bioinformatic tools have helped decode the genomes of tens of thousands of … of microbial genomes directly from environmental sequence data, by piecing each genome together from large mixtures of …

… in fungi. The Science Changing an A, C, T or G in a genome sequence can lead to changes in protein structures … 5mC is an important piece of how they regulate their genomes, but is not well understood in fungi. A team of … genome-wide regulation and cataloging them in JGI’s fungal portal MycoCosm. …

… exposure to working with Streptomyces, learning more about genome mining, as well as isolation and a little bit of … them are actinobacteria. And so we get a lot of them from databases of organisms, so things like the NRL database - or online catalog, I guess. So we've also been …

… Genomics Building (IGB) seen above is home to the DOE Joint Genome Institute (JGI). Researchers from the DOE Systems … Biology Knowledgebase (KBase), the National Microbiome Data Collaborative (NMDC), and Berkeley Lab Biosciences Area … The vision of the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science user …

… determination. Rhondene Wint, an alumna of the DOE Joint Genome Institute (JGI)-UC Merced internship program and … ecosystem,” said Salamov, one of Wint’s mentors and a data scientist at the JGI. Previous studies were conducted … predictor of gene expression levels using machine learning tools. “This was very exciting to see how Rhondene not only …

… in giving a voice to JGI users who feel that certain data sharing policies fail to represent the needs of large … unaware that [public but use-restricted] exist on [the JGI data portal] IMG or how to deal with situations in which they …

… related to our Integrated Microbial Genomics & Microbiomes portal. …