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An Age of CRAGE: Advances in Rapidly Engineering Non-model Bacteria
A group led by JGI scientists have made strides in improving and applying a method that allows researchers to quickly … the cover of ACS Synthetic Biology. (Wayne Keefe/Berkeley Lab) For example, the JGI first used CRAGE to engineer …
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Here, There and Everywhere: Large and Giant Viruses Abound Globally
… diversity of large and giant viruses. While the microbes in a single drop of water could outnumber a small city’s … Science User Facility located at Lawrence Berkeley National Laboratory (Berkeley Lab) uncovered a broad diversity of …
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How Filamentous Fungi Sense Food
Tracing gene regulatory networks in the model fungus  Neurospora crassa . The Science A team … sources, these fungi detect which complex chains are available; this information triggers pathways to determine which …
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For the Tiniest Archaea, A Genomic Switch of Friend or Foe
Meta-omics datasets show that CRISPR-Cas systems determine mutualism or parasitism between some archaeal hosts and their hitchhikers. The Science Within the archaeal domain, there is a group of tiny … these symbiotic interactions are difficult to study in the lab. Metagenomics provides new views of these …
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Designer DNA: JGI Helps Users Blaze New Biosynthetic Pathways
… enabled by the JGI DNA Synthesis Science Program. Fashioning DNA outside a cell is key to interrogating what genes … Science User Facility located at Lawrence Berkeley National Laboratory (Berkeley Lab), comes in. The JGI is uniquely … and construction, providing a unique resource for the international community and fostering academia-industry …
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An Automated Tool for Assessing Virus Data Quality
… fragments and data quality. The Science Through advances in sequencing technologies and computational approaches, … virus sequences vary widely. In a previous effort, an international consortium recommended specific guidelines and … Science User Facility located at Lawrence Berkeley National Laboratory (Berkeley Lab), has developed a command-line tool …
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Streamlining Regulon Identification in Bacteria
RIViT-seq technology could speed up associating transcription factors with their target genes. The … that can be turned on or off by the same regulatory protein. Researchers demonstrated the efficacy and potential of … Science User Facility located at Lawrence Berkeley National Laboratory (Berkeley Lab). Transcription factors control …
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Supercharging SIP in the Fungal Hyphosphere
High-throughput stable isotope probing helps ID novel interactions between bacteria and fungi The Science … stable isotope probing (SIP) proved to vastly reduce labor and improve results. Applying this method to the study …
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JGI@25: Mapping Switchgrass Traits with Common Gardens
In honor of the JGI's 25th anniversary in 2022, we have revisited a number of notable achievements that showcase our collaborations and capabilities to enable great science that …
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Fields of Breeders’ Dreams: A Team Effort Toward Targeted Crop Improvements
… around the country recognize that crop varieties grow best in certain regions. Most plant species have adapted to their local … decades to develop new crops. One example is an ongoing collaborative effort to improve the emerging bioenergy crop …
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Ian Blaby
Since 2019 Dr. Blaby heads the DNA synthesis platform at the Joint Genome Institute, where he leads three groups focused on … Frontiers in Bioengineering and Biotechnology. 11. 2023 Liu et. al., Bacterial genome editing by coupling …
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JGI at the AGU Fall Meeting
This year the AGU Fall Meeting, with the theme “Science is Society,” hosts sessions in … research and tips for submitting successful proposals: Collaborate With a U.S. DOE User Facility: Learn About … thousands of newly sampled microbial genomes from North American watersheds (Invited)” 4pm CST Convention Center, …
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