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Streamlining Regulon Identification in Bacteria
… with their target genes. The Science Regulons are a group of genes that can be turned on or off by the same regulatory … one type of RNA polymerase responsible for each gene. These bacterial RNA polymerases are made up of a core enzyme … the 5’-ends by 5’-end sequencing, from which those promoter sequences recognized by a given sigma factor are inferred. …
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Getting to the Bottom of Fungal Functions Across Earth’s Forests
… registers the sound — one thing is for sure: there are lots of fungi around. Within a forest’s soil, hundreds of species … at Lawrence Berkeley National Laboratory (Berkeley Lab) sequenced 1 trillion bases — a terabase — of soil RNA for … fungi in these environments. “Now with these new tools — metatranscriptomics, RNA sequencing of soil RNA — we can …
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Viruses Reprogram Cells into Different Virocells
… from The Ohio State University and the University of Michigan studying how virus infections cause significant … was done by the JGI, and proteomics and metabolomics analysis and microscopy at EMSL. The team infected the … approach to infecting and metabolically reprogramming the bacterial host, which was transformed into two very …
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JGI Early Career Researchers Featured in mSystems Special Issue
… In a special issue of mSystems , out May 14, 2019, JGI researchers are among … recent Nature Communications paper, uncovering giant virus sequences in soil for the first time. A second approach … can develop high-throughput and high-resolution studies of interactions between host cells and viruses in the …
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An Addiction Crucial to a Fungus’ Reproduction
… A fungus relies on bacteria to regulate key components of its reproductive machinery The Science To better … reproduction, and the reproductive genes they regulate. The bacterial endosymbiont, Burkholderia , is recognized as a … with the fungi and bacteria, while the DOE JGI team sequenced and annotated a host genome (Rm ATCC 52813) as …
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Elviz – exploration of metagenome assemblies with an interactive visualization tool
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Rapid Evolution of Coral Proteins Responsible for Interaction with the Environment
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Plant–microbiome interactions: from community assembly to plant health
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Metabolite release by nitrifiers facilitates metabolic interactions in the ocean
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Hydrophobins from Aspergillus Mediate Fungal Interactions with Microplastics
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Supercomputing, MetaHipMer and the Mega Dataset of Lake Mendota
… before. In 2006, the JGI produced 33 billion base pairs of sequence; by 2023, that number was almost 717 trillion. … also collaborated to advance computing infrastructure and analysis. This way, JGI users — both primary, … integrated high-throughput sequencing and computational analysis that enable systems-based scientific approaches to …
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Interdisciplinary delegation from the University of Duisburg-Essen explores collaborative opportunities with Lawrence Berkeley National Laboratory
… A two-day kick-off meeting held at Lawrence Berkeley National Laboratory … be measured by IR-spectroscopy and mass spectrometry in sequence in real time at an atomic resolution. We are … as it aligns well with DOE’s missions and the JGI’s algal focus.”  To bolster the already existing …
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