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Boosting Small Molecule Production in Super “Soup”
Do metabolic pathways from engineered yeasts still work in cell-free environments? … yeast cells but then moves out of the cell structure into a cell-free system. The work complements efforts to … CRISPR-Cas9 that enhanced their ability to redirect the carbon in the cells toward particular pathways. In this …
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Natural Prodcast Episode 3: The Primer, Part 3
… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s … and you can still make more of it, then you start going into human trials or animal trials first, and going through … ALISON: There we go. Okay.  DAN: So DNA is transcribed into RNA in the cell. That’s the “message” that comes from …
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Mission
… by the Biological and Environmental Research program, the Joint Genome Institute provides advanced genomic capabilities, … strains, or enzymes to convert plant biomass components into fuels, chemicals, and bioproducts, or to control … that can convert lignocellulosic-derived sugars or lignols into biofuels or other bioproducts currently produced from …
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Bacteria and Fungi Divvy Up the Work in Forest Floor
… nutrient. The Impact This study is the first to dig into a forest floor ecosystem to discover what carbon- and nitrogen-metabolizing enzymes are abundant, and … to which microbes they belong. This study provides further insights into the microbial involvement in carbon and …
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New Research Sheds Light on Diversity in the Deep Sea
Microbial communities living near hydrothermal deep-sea vents hold vast potential for … hydrothermal fluid. Eventually, that fluid is expelled back into the ocean through vents at temperatures that can exceed … nitrogen metabolism, as well as those that play a role in carbon cycling. However, the high degree of variability in …
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The Expanding Universe of Methane Metabolisms in Archaea
Metagenome-assembled archaeal genomes provide new insights into an ancient metabolism. Methane is a greenhouse gas 20 times more potent than carbon dioxide. Billions of years ago, methane-producing …
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Ian Blaby
Since 2019 Dr. Blaby heads the DNA synthesis platform at the … with a zinc-mirror heme site ties heme availability to carbon metabolism in cyanobacteria Nature Communications … analysis of nitrogen starvation–induced modifications of carbon metabolism in a Chlamydomonas reinhardtii starchless …
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Simon Roux Named 2025 ASM Microbiome Data Prize Awardee
Congratulations to US Department of Energy (DOE) Joint Genome Institute (JGI) staff scientist Simon Roux , who was … Microbiology (ASM). Roux leads the Viral Genomics group within the JGI Metagenome Program, and coordinates the …
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Sequencing Sphagnum Leads to Discovery of Sex Chromosomes
A nuanced understanding of peat moss drives insight into carbon storage   The …
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Natural Prodcast Episode 4: Nancy Keller
… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s … I wanted to start, maybe just by asking you how did you get into the field of natural products?   NANCY: Yeah, that’s a … was finished with the Peace Corps, I decided I wanted to go into international agriculture. I had really changed my …
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JGI@25: Building a Better Bean
In honor of the JGI's 25th anniversary in 2022, we have … plays an important role in soil health through nitrogen-fixation and holds clues for maximizing soybean, the common … seemingly humble common bean has fueled further research into disease tolerance in crops, drought- and …
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Better Genome Editing for Bioenergy
… part of CRISPR-Cas9 technology to enable improvements in microbial oil production. The Science CRISPR-Cas9 is a … and genes that lead to increased lipid production. These insights into  Y. lipolytica biology and lipid metabolism furthers …
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