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An Enzyme System to Help Catalyze Bioproduction of Plastic
… By characterizing the structure and function of a … an enzyme system that was previously only understood at a genetic level. Functional and structural experiments showed … The U.S. Department of Energy Joint Genome Institute, a DOE Office of Science User Facility located at Lawrence …
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Getting to the Bottom of Fungal Functions Across Earth’s Forests
… registers the sound — one thing is for sure: there are lots of fungi around. Within a forest’s soil, hundreds of species … soil RNA to fungal genomes.  The U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at …
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Training the Next Generation of Talent
… DOE JGI, UC Merced Days after presenting the results of his summer research at the U.S. Department of Energy … Distinguished Graduate Internship Program. Conceived by Wang and Visel, the program challenges UC Merced graduate … could be considered.” Olmstead’s project focused on the genetic mechanisms of chemotaxis in the Arabidopsis …
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Here, There and Everywhere: Large and Giant Viruses Abound Globally
… JGI-led team significantly expands the global diversity of large and giant viruses. While the microbes in a single … to over 900,000 proteins, and virus diversity in this group expanded 10-fold from just 205 genomes, redefining the phylogenetic tree of giant viruses. Metabolic Reprogramming a …
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Analyze Data
… The JGI supports the entire data life cycle — from experimental … The JGI is involved in efforts to integrate data in support of new research questions that span domains. We also work with our partners to build infrastructure in support of new analysis techniques.  …
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Iron-rich Microbial Mats’ Main Players: Marsarchaeota
… early Earth conditions. The Science Through a combination of sequencing tools and techniques applied to samples … found in iron-oxide microbial mats. The reddish hues caused by the presence of iron led Inskeep and his colleagues to name the archaeal lineage for the planet Mars. To help determine where Marsarchaeota might fall …
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Examples: Successful LOIs & Submissions
… See below for examples of successful Letters of Intent to our Community Science Program Large-Scale Call, … Elucidating Sphagnum microbiome genetic interactions for improved growth at elevated … strategies in a cosmopolitan and abundant soil bacterium: genetic microdiversity or core metabolic flexibility? …
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The Surprising Structure of a Shrub Willow Sex Chromosome
… A genetic architecture that is characteristic of the sex chromosomes of mammals is, for the first time, … to correct mutations. This process, called gene conversion, helps maintain the integrity of the sequences. The … out in particular: a cytokinin response regulator that was expanded in a palindrome and shown to be undergoing gene …
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Doubling Down on Known Protein Families
… online Oct. 11, 2023 in  Nature highlights the vast array of functional diversity of microbes through a novel approach to better understand microbial communities by looking at protein function within them. The work was led … sequencing allows researchers to study the entire genetic makeup of these communities via whole genome …
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A One-Stop Shop for Analyzing Algal Genomes
… data portal allows anyone to freely investigate the genes of more than 100 algae. The Science Interested in the … of algae? You now have one place where you can browse the genetic blueprints of these photosynthetic organisms. … MycoCosm for comparative analysis of fungal genomes, and Phytozome for comparing plant genomes. Kuo and Grigoriev …
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Engagement Webinar: Harnessing JGI’s Metabolomics Capabilities
… (CSP) . This includes mass spectrometry-based measurements of primary and secondary metabolites from plants, … resources. Q:  Where can I get information for funding by JGI? A: The JGI is not a funding organization. Rather, it … data (secondary metabolomics), how can we map it into these networks? A: We use networks based on the fragmentation …
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User Support Analysis Group
… computational analysis for new technology development and JGI user science projects. We perform analysis for diverse … epigenomics. Our work varies in scope from the development of highly customized analysis workflows for new product types, to the development of automated analysis pipelines for standard sequencing …
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