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Enhancing Terminal Deoxynucleotidyl Transferase Activity on Substrates with 3′ Terminal Structures for Enzymatic De Novo DNA Synthesis
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A Single Nucleotide Change in the polC DNA Polymerase III in Clostridium thermocellum Is Sufficient To Create a Hypermutator Phenotype
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Aspects of the Neurospora crassa Sulfur Starvation Response Are Revealed by Transcriptional Profiling and DNA Affinity Purification Sequencing
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DNA affinity purification sequencing and transcriptional profiling reveal new aspects of nitrogen regulation in a filamentous fungus
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Better Genome Editing for Bioenergy
… at a genetic level, how does  Y. lipolytica work? The project was a multi-institutional effort led by … Joint Genome Institute (JGI), a DOE Office of Science User Facility. Y. lipolytica is a tantalizing microbial … sgRNA sequences: six for every gene in the genome. The JGI  DNA Synthesis Science team synthesized these sgRNAs, cloning …
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JGI Announces 2025 New Investigator Portfolio
… researchers) Each year, the JGI searches for novel research projects from PIs who have not led any previously accepted … capabilities such as metatranscriptomics and environmental DNA sequencing to explore microbial and plant interactions … for this ongoing call; the next deadline for proposal submission is Sept. 9, 2025, for inclusion in the November …
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Len Pennacchio
In 2003, Dr. Pennacchio joined the DOE Joint Genome Institute … Data Generation Platforms (Sequencing, Single Cell, DNA Synthesis, and Metabolomics) as well as Research & … Additional duties of this Deputy include interacting with users seeking to exploit new genomic technologies and …
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Graduate Students Get Thesis Research Opportunity at the JGI
… at one of the DOE national laboratories or national user facilities. As a result of the latest call , a total of … between 3-12 consecutive months. Their proposed research projects address scientific challenges central to Office of … mission areas across the 6 Office of Science research programs. Among the recipients of the latest SCGSR award is …
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Fungal Endophytes of Populus trichocarpa Alter Host Phenotype, Gene Expression, and Rhizobiome Composition.
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Kingdom-Wide Analysis of Fungal Protein-Coding and tRNA Genes Reveals Conserved Patterns of Adaptive Evolution
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Fungal community assembly in drought-stressed sorghum shows stochasticity, selection, and universal ecological dynamics
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A fungal transcription factor essential for starch degradation affects integration of carbon and nitrogen metabolism
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