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Coevolution of the Ess1-CTD axis in polar fungi suggests a role for phase separation in cold tolerance
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Ben Bowen
… BS – University of Arkansas, Fayetteville, Chemical Engineering Ph. D. – … 2024 Berkeley Lab Recognition of Excellence Award 2016 R&D 100 Winner 2014 Berkeley Lab … T., Ruebel, O., Northen, T., & Bowen, B. (2015). Analysis of metabolomics datasets with high-performance computing and …
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Climate Change Threatens Base of Polar Oceans’ Bountiful Food Webs
… tiny algae. The cold polar oceans give rise to some of the largest food webs on Earth. And at their base are … photosynthetic algae. But human-induced climate change , a new study suggests, is displacing these important cold-water … communities occurs in moderate waters that have an average surface temperature of about 58° Fahrenheit (14° …
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Gut Fungi: Unexpected Source of Novel Chemicals
… The Science Anaerobic fungi, which die in the presence of oxygen, dwell in herbivore guts and help them digest … meal. In their evolutionary history, these fungi branched off early from aerobic fungi, which can breathe oxygen — … can whip up dozens of complex natural products, including new ones. The Impact In the past, natural products have been …
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Ray Turner Completes Last Tour of Lab Duty at JGI
… as a typical monthly JGI All-Hands Meeting, after a couple of perfunctory items, the agenda went off the rails – according to plan but … Ray and it has been especially called on in the move to the new building where that was really critical. It takes a … The U.S. Department of Energy Joint Genome Institute, a DOE Office of Science …
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The genome of the xerotolerant mold Wallemia sebi reveals adaptations to osmotic stress and suggests cryptic sexual reproduction
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JGI-UC Merced Interns Share Their 2021 Experiences
… During the summer of 2021, 13 interns from UC Merced spent eight weeks working … in their academic career enjoyed the chance to develop new skills needed for their PhD research. And for the first … in this program’s history, two interns returned to re-engage with their mentors from the previous year and continue …
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UC Merced Interns Reflect on Their JGI Summer Projects
… Over the course of eight weeks this past summer, 10 students from UC Merced … students worked on ranged far and wide — from implementing new data visualization tools, to using natural language processing techniques to categorize genetic information. … Babu (undergraduate) Mentor: Zhong Wang Click the image to watch the video …
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Better Genome Editing for Bioenergy
… A team has optimized a crucial part of CRISPR-Cas9 technology to enable improvements in … tool will make the right cut, researchers created a set of guide RNAs that were effective against 94 percent of the … and xylose — into fatty acids that could be used for renewable fuel. In fact, lipids can make up more than 90 …
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Extracting the Secrets of Secondary Metabolites
… CRAGE-CRISPR combo helps further demystify biosynthetic gene … survival, may now be easier to characterize following a proof-of-concept study in which researchers paired CRISPR and … luminescens and its secondary metabolites work could yield new tools for pest control. Secondary metabolites are highly …
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Engagement Webinar: Harnessing JGI’s Metabolomics Capabilities
… The JGI Engagement Webinar held November 5, 2020 (watch the  video … (CSP) . This includes mass spectrometry-based measurements of primary and secondary metabolites from plants, … long does it take to do all the analyses? A:  For the JGI  New Investigator and  Functional Genomics proposal calls, …
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JGI Earth Month: The Unusual Metabolism That Helps Plants Withstand Drought
… In April 2020, we mark both the 50th celebration of Earth Day on April 22, and DNA Day on April 25. As both …   ALISON:  Hey! I’m Alison Takemura at the US Department of Energy Joint Genome Institute, or JGI.  Two special days … need. Karolina is working to better understand what genetic features make CAM possible. So, she’s studying yuccas, a …
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