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Uncovering Novel Genomes from Earth’s Microbiomes
… for multiple applications.       Despite advances in sequencing technologies and computational methods in the … and press a button to build a model from our database of mappings between biochemical reactions and annotations. We …
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Enlarging Windows into Understanding Gene Functions
JGI innovates protocol revealing how genetic variations in … a dizzying array of combinations, are unremarkable, save perhaps for the absence of all the other letters of the …
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2022 Progress Report
Pictured is a timelapse of the Integrative Genomics Building (IGB) seen above is home to the DOE Joint Genome Institute (JGI). Researchers from the DOE Systems …
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Gene Expression: From On-Off Switch to Dial
Fine-tuning metabolic gene expression helps identify variants in yeast genes. The Science Scientists have developed a more nuanced library approach to tuning gene expression in metabolic pathways. Compared to the …
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Genome Sequence of Kosmotoga olearia Strain TBF 19.5.1, a Thermophilic Bacterium with a Wide Growth Temperature Range, Isolated from the Troll B Oil Platform in the North Sea
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Climate Change Threatens Base of Polar Oceans’ Bountiful Food Webs
… warm-adapted microbes edge polewards, they’d oust resident tiny algae. The cold polar oceans give rise to some of the … than previously suspected. “That would cause significant consequences on the entire food web, and therefore ecosystem … After isolating the algal communities on filters, they sequenced DNA ‘marker’ gene sequences to identify the …
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High quality draft genome sequence of the slightly halophilic bacterium Halomonas zhanjiangensis type strain JSM 078169T (DSM 21076T) from a sea urchin in southern China
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Community Science Program
… community at large with access to high-throughput sequencing, synthesis, and metabolomics at the JGI for projects of … based on their DOE relevance.  For accepted proposals, sequencing, synthesis, metabolomics and analysis will be …
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Biochemical characterization of Fsa16295Glu from “Fervidibacter sacchari,” the first hyperthermophilic GH50 with β-1,3-endoglucanase activity and founding member of the subfamily GH50_3
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JGI@25: The Human Genome Project, or the JGI’s Origin Story
In honor of the JGI's 25th anniversary in 2022, we have … conditions. While scientists around the world were busy sequencing the human genome, an arms race was being waged. … Genome Institute. Hear her memories of what it was like sequencing around the clock and see some of the physical …
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Experimenting with EcoFABs for Student Labs - Jill Bouchard & Ying Wang
… compare their work consistently. And EcoFABs also work well in the classroom. This episode, we visit Los Medanos Community College to see EcoFABs in action in Jill Bouchard’s BIO 21 lab course. …
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How to Target a Microbial Needle within a Community Haystack
A workflow for capturing the genetic make-up of specific uncultivated microbes … The Impact Despite great strides in generating genome sequences for members of the microbial world through bulk community sequencing (metagenomics) and single-cell genomics, the vast …
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