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From Intern to Published Scientist: The Journey of a JGI-UC Merced Intern
… determination. Rhondene Wint, an alumna of the DOE Joint Genome Institute (JGI)-UC Merced internship program and … current PhD student, reached this milestone with a recent publication in Molecular Biology and Evolution . “It’s my … a gene sequence-based predictor of gene expression levels using machine learning tools. “This was very exciting to see …
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Climate-driven divergence in plant-microbiome interactions generates range-wide variation in bud break phenology
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JGI@25: Mapping Switchgrass Traits with Common Gardens
… crop. In 2018, the JGI had sequenced and assembled the genomes of two varieties of a close relative and model … productivity across 1,100 miles and eight states. In 2021, using switchgrass samples from these gardens, a team led by … reference genome built off more than a decade of work; as sequencing technologies advanced, assembly and annotation of …
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Hiroshi Otani
… Since joining the DOE Joint Genome Institute in 2016, Dr. Otani has been studying secondary metabolism in … activity is focused on developing and implementing new technologies and methodologies that facilitate discovery of … in bacterial RiPP biosyntheses. J Ind Microbiol Biotechnol. 2023 Feb 17;50(1):kuad005. Otani H, Udwary DW, Mouncey NJ. …
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Evolution of a Fungal Gene Expression Regulator
… in fungi. The Science Changing an A, C, T or G in a genome sequence can lead to changes in protein structures … of specific 5mC methyltransferase (MTase) variants. Using new sequencing technologies for producing both reference genomes … The work conducted by the US Department of Energy Joint Genome Institute, a DOE Office of Science User Facility, is …
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Streamlining Regulon Identification in Bacteria
… sigma factors that initiate transcription in bacteria. Using this technology, which combines an in vitro … in Streptomyces coelicolor . The Impact As an integrative genome science user facility, connecting genes to functions … assay. The second step consists of RNA sequencing of whole transcriptomes, and the third is determining the …
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Genomic profiles of four novel cyanobacteria MAGs from Lake Vanda, Antarctica: insights into photosynthesis, cold tolerance, and the circadian clock
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Dan Rokhsar
… Dr. Rokhsar joined the JGI in 2000 as the founding Associate Director for Computational … and led the computational efforts directed towards the sequencing, annotation, and analysis of three human chromosomes. After successful completion of the Human Genome Project, Professor Dr. Rokhsar ’s team has continued …
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Proposed design of distributed macroalgal biorefineries: thermodynamics, bioconversion technology, and sustainability implications for developing economies
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Decoding the massive genome of loblolly pine using haploid DNA and novel assembly strategies
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Single cell genomic and transcriptomic evidence for the use of alternative nitrogen substrates by anammox bacteria
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Functional Genomics of Novel Secondary Metabolites from Diverse Cyanobacteria Using Untargeted Metabolomics
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