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Controlling selectivity of modular microbial biosynthesis of butyryl-CoA-derived designer esters
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Engineering promiscuity of chloramphenicol acetyltransferase for microbial designer ester biosynthesis
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Thermochemical wastewater valorization via enhanced microbial toxicity tolerance
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New keys to unlock the treasure trove of microbial natural products
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JGI announces 2023 CSP Functional Genomics awardees
… and omics capabilities to enhance understanding of gene and genome function.  Below find a list of the six researchers …
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JGI announces 2024 Functional Genomics awardees
… and omics capabilities to enhance understanding of gene and genome function. Tapping into these functions allows …
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You Can Move, But You Can’t Hide
Lead Nikos Kyrpides at the U.S. Department of Energy Joint Genome Institute, a DOE Office of Science User Facility at … in soils and water. MGEs like viruses and plasmids drive microbial processes and evolution. This is because MGEs can … and their evolution at the cellular level, scientists can better understand ecosystem-wide processes. Summary geNomad …
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JGI@25: Expanding Metagenomics to Capture Viral Diversity
… because they often need unique conditions and a specific microbial host to replicate. Sequencing genetic material … Beginning in the early 2000s , these environmental metagenomes began to offer a window into viral existence. Along … for viruses, so researchers around the world would have better, easier access to these viral genomes. The new …
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An Age of CRAGE: Advances in Rapidly Engineering Non-model Bacteria
… that allows researchers to quickly modify diverse bacterial genomes. In 2019, the JGI’s Yasuo Yoshikuni and his team  … Mouncey. Using CRAGE, JGI has established a portfolio of microbial hosts that users can select to be engineered. … used with the model plant  Arabidopsis,  the plants grew better than when they were grown with non-engineered …
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The Power of One, Amplified
… cells harbored mobile genetic elements that were missed within paired metagenome assembled genomes (MAGs), and that dominant … of bioinformatics tools for  extracting snippets of microbial genomes directly from environmental sequence data, …
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Virus-Microbe Interactions of Mud Island Mangroves
… laboratories or national user facilities. Baker had worked with the JGI through a Community Science Program (CSP) … research builds on that. “The purpose of this CSP is to better understand methane cycling in mangrove wetlands in … Rambo’s work was overseen by Susannah Tringe, head of the Microbial Systems group. He also worked with Simon Roux and …
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Here, There and Everywhere: Large and Giant Viruses Abound Globally
… archaea and eukaryotes, and they range in particle and genome size from small, to large and even giant. The genomes … noted study senior author  Tanja Woyke , who heads JGI’s  Microbial Program . The team mined more than 8,500 publicly … reprogramming, Schulz explained, makes the host function better under certain conditions, which then helps the virus …
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