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A Revamped Amplification Method that Enables Nearly Complete Single-Cell Genomes
… from single cells. The Science Studying the  genomes of microorganisms is incredibly useful for understanding the … years, extracting single cells and then amplifying their DNA for genome sequencing was no easy task. The traditional … way of collecting them is through a method called Multiple Displacement Amplification, and most genomes that …
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JGI@25: The Little Alga That Could
… In honor of the JGI's 25th anniversary in 2022, we have revisited a … sequences have been cited in almost one-fourth (23.8%) of publications focused on that specific algae. The reference … Chlamydomonas has this related protein that’s also causing DNA damage,” Merchant said, “that something is wrong with …
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Natural Prodcast Episode 9: Roger Linington
… DAN: Welcome back for episode 9 of Natural Prodcast. This week, Alison and I talk to Roger … And that’s been followed by developments in pulse sequences and improvements in the ways in which you acquire … to hear from you! We have projects in genome sequencing, DNA synthesis, transcriptomics, metabolomics, and natural …
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How Maize Makes An Antibiotic Cocktail
… Maize produces a family of compounds that protects it against infections — using … enzymes. The Science Maize ( Zea mays ) produces a plethora of antibiotics called zealexins. Even though scientists have … terpene synthases and cytochrome P450s — that catalyze multiple products, resulting in many antibiotics. To uncover …
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Integrative visual omics of the white-rot fungus Polyporus brumalis exposes the biotechnological potential of its oxidative enzymes for delignifying raw plant biomass
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Cultivating Symbiotic Antarctic Microbes
… not free-living organisms. The Science Researchers employed multiple microbiology and ‘omics techniques to … The Impact The Antarctic lakes are a “treasure trove” of unknown microbes that play critical roles in … region in the SPEARE proteins appears to be involved in DNA degradation, and these proteins may be directly involved …
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Doubling Down on Known Protein Families
… online Oct. 11, 2023 in  Nature highlights the vast array of functional diversity of microbes through a novel approach … Laboratory (Berkeley Lab), and collaborators across multiple other research centers around the world. “We’ve … those with pivotal applications in biotechnology, such as DNA editing enzymes.” Leveraging Protein Families in a New …
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RECAP: Multi-Omic Journeys with 2023 JGI Annual Meeting Keynotes
… 21-23, 2023, attendees joined the JGI Annual Genomics of Energy & Environment Meeting.  A wide array of invited speakers shared how research infrastructure – DNA sequencing, synthesis, metabolomics, data analysis, and … these amazing technologies that the JGI has to identify and sequence who’s making what, that the context at a microscale …
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Sequencing and functional validation of the JGI Brachypodium distachyon T‐DNA collection
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Dan Rokhsar
… directed towards the sequencing, annotation, and analysis of three human chromosomes. After successful completion of the Human Genome Project, Professor Dr. Rokhsar ’s team … and animals by combining computational genome analysis, sequence-based genetic methods, and comparative …
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Novel metabolic interactions and environmental conditions mediate the boreal peatmoss-cyanobacteria mutualism
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Carotenoid–protein interaction alters the S1 energy of hydroxyechinenone in the Orange Carotenoid Protein
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