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… The focus of this group, in recent years, has been to bring … The developed strains represent an additional phase of user-accessible project types, in which DNA-based … chromosomally integrated into a taxonomically diverse suite of microbial chassis strains for elevated opportunity for …

… as user facility that aims to provide access to state-of-the-art DNA synthesis and assembly technologies to the … mining and sequence design with scaling the production of large, difficult to synthesize constructs such as those … in new technologies, in particular through adoption of lab automation enabling ever-higher levels of throughput. …

… Software engineers in the Synthetic Biology Informatics Group develop, deploy, and maintain software that support the JGI’s Synthetic Biology Program .  Representative software includes: gRNA-SeqRET , an organism-agnostic CRISPR …

… Our lab is using mass spectrometry based metabolite profiling to provide direct biochemical datasets to improve our understanding of microbial metabolism. Of particular interest is understanding the distributed and …

… In honor of the JGI's 25th anniversary in 2022, we have revisited a … genes with other organisms (a third of those shared by both humans and flowering plants). Its genome also contains … sequences have been cited in almost one-fourth (23.8%) of publications focused on that specific algae. The reference …

… ( CRAGE ). CRAGE enables scientists to insert large pieces of DNA (up to 60 kb) in a single step, directly into the genome. “CRAGE is central to our ability to offer host-engineering for our users,” says JGI Director … (BGCs). BGCs make diverse molecules of value to both human and ecosystem health. But bacteria often fail to …

… Populations of Antarctic lake microbial communities change with the … with light availability. A long-running time-series study offers a first glimpse into a full season’s cycle of this polar environment. This cycle suggests a reliance on … (project 4031). The work conducted by the US Department of Energy Joint Genome Institute, a DOE Office of Science …

… Pictured is a timelapse of the Integrative Genomics Building (IGB) seen above is … Area are also co-located in the IGB. Vision The vision of the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office …

… fungal infections. That’s why Mars, Inc., a maker of chocolate for more than 100 years and one of the world’s largest buyers of cocoa, is collaborating with others to develop healthier … The U.S. Department of Energy Joint Genome Institute, a DOE Office of Science …

… The JGI and EMSL are U.S. Department of Energy (DOE) Office of Science national scientific user facilities dedicated to … Click to view a downloadable copy of the sponsor prospectus … Keynote Speakers Jim Collins Massachusetts Institute of Technology Kristala Prather Massachusetts Institute of …