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Extracting the Secrets of Secondary Metabolites
… to integrate large genetic payloads directly into diverse microbes. Combining CRAGE with CRISPR provides researchers … the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at … CRISPR to knock out or activate genes, researchers at the JGI were able to monitor loss- and gain-of-function. The …
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Supercharging SIP in the Fungal Hyphosphere
… it. The isotopes are incorporated into the DNA of specific microbes who consume the labeled food or water. Later, their … which microorganisms used the labeled substance and which microbes did not. This is normally an arduous wet lab … HT-SIP is a capability available to request through  the JGI proposal calls . … Work at Lawrence Livermore National …
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High Five: Celebrating the JGI-UC Merced Genomics Internship Program
UC Merced students have contributed to the research of 13 JGI scientists since the program’s inception. In 2014, JGI’s … saying, “I wish Akshay could stay at the JGI for another 6 months! In a very short time his incisive questions, … Clarissa Nobile, investigating interactions between microbes and venomous hosts. She also facilitates the …
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Operating Expenses
FY2023 Spending Profile The JGI is funded primarily by the DOE Office of Biological and …
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Genome Insider
Genome Insider is a podcast that showcases the work of JGI collaborators in brief forays, connecting audiences with … to contribute to a more sustainable world. Learn about JGI-supported projects, delving into the researchers’ …
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VEGA Symposium
Hosted by the JGI and co-organized with NIST,  the goal of the Viral … Libusha Kelly , Albert Einstein College of Medicine JGI Organizers Simon Roux, Jonelle Basso, Maureen Berg, …
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The Megadata of Lake Mendota - Part 1: Many, Many Mers
Madison. And Trina McMahon's lab has been sampling the microbes of that lake for over 20 years, to understand how … to analyze 500 metagenomes, it was the biggest project the JGI had ever put together.  The next 3 episodes are the …
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Simon Roux Named 2025 ASM Microbiome Data Prize Awardee
… to US Department of Energy (DOE) Joint Genome Institute (JGI) staff scientist Simon Roux , who was recently selected … (ASM). Roux leads the Viral Genomics group within the JGI Metagenome Program, and coordinates the development of … analysis to better characterize how viruses infect soil microbes and influence how soil ecosystems function. He was …
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SIPs with Standards
… microbial communities. These experiments can show which microbes are handling specific nutrients, or what they're … catch: SIP labwork and analysis can be very demanding.  The JGI offers SIP analysis to make these experiments accessible … multiple teams and analyses. This episode, Rex Malmstrom (JGI), and Roli Wilhelm (Purdue University), share a few …
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User Support Analysis Group
… computational analysis for new technology development and JGI user science projects. We perform analysis for diverse …
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Tanja Woyke
… of User Program position in 2021. In addition to her JGI appointment, she also holds an Adjunct Scientist … provides direction, leadership and oversight for all of the JGI user programs, including the Community Science Program … 20: 721 Nayfach et al. 2021. A genomic catalog of Earth’s microbiomes. Nature Biotechnology 39, 499-509. …
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Nikos Kyrpides
Nayfach S, et al. (2021) A genomic catalog of Earth’s microbiomes. Nature Biotechnol . 39(4):499-509 Danko … . 39:578-585 Nayfach S. et al. 2021. A genomic catalog of Earth’s microbiomes. Nature Biotechnol . 39:499-509. … inoviruses are pervasive in bacteria and archaea across Earth’s biomes. Nature 4:1895-1906 Sberro H. et al. 2019 …
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