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Enlarging Windows into Understanding Gene Functions
JGI innovates protocol revealing how genetic variations in sequences affect traits. In a text file, the rows of … Laboratory (Berkeley Lab). And one of the tools that researchers can apply to study the transcription factors … in the genome by adding tagged transcription factors to a genomic DNA library. “It’s an innovative way to rapidly …
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For the Tiniest Archaea, A Genomic Switch of Friend or Foe
… interactions are difficult to study in the lab. Metagenomics provides new views of these relationships.  Recently , researchers used population genomics to find that while … harbored self-targeting CRISPR systems, metabolic modeling showed that  Ca . Huberiarchaeum would help fill in …
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Petra Byl
Petra is an affiliate researcher who cultivates marine algae infected by giant … from subtropical, oligotrophic ocean gyres. She uses genomic and transcriptomic sequencing along with laboratory manipulations to understand how nutrient …
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JGI@25: A Single Cell, Myriad Microbial Discoveries
In honor of the JGI's 25th anniversary in 2022, we have … help solve energy and environmental challenges. In 2009, researchers at the JGI and the Bigelow Laboratory for Ocean … Sciences described a novel technique to access high-quality genomic information using minute quantities of DNA derived …
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Better Genome Editing for Bioenergy
… technology to enable improvements in microbial oil production. The Science CRISPR-Cas9 is a powerful, high-throughput … To ensure the gene editing tool will make the right cut, researchers created a set of guide RNAs that were effective … study,  published in  Metabolic Engineering , a team of researchers likewise honed their tool before felling their …
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Neha Varghese
… bioinformatics software to enable analysis and interpretation of genomic and metagenomic data for JGI’s user community. She also provides …
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Jane Grimwood Named HudsonAlpha Genomics Chair
Congratulations to Jane Grimwood, who has been appointed the Loretta Purdy Spencer Chair in Genomics at the HudsonAlpha Institute for Biotechnology! … plant genomes. She has appeared on the annual Highly Cited Researchers list assembly by Clarivate Analytics. In 2020, …
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Crysten Blaby-Haas
… between JGI and the Molecular Foundry, a nanoscale research and knowledge-based user facility at Berkeley lab. … University of Florida, working with Valérie de Crécy-Lagard on using comparative genomics to predict gene function in bacteria and leveraging …
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JGI@25: Building a Better Bean
… bean’s close relative, as a biofuel. To this end, a team of researchers led by Jeremy Schmutz of the JGI and the … specifically, “[At the JGI] we do use Phaseolus as a test model quite frequently for R&D in plant genomics, because it is an inbred dicot,” Schmutz explained, …
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An Age of CRAGE: Advances in Rapidly Engineering Non-model Bacteria
… made strides in improving and applying a method that allows researchers to quickly modify diverse bacterial genomes. In … a fluorescent marker into  E. coli , allowing the team to model the competition dynamics between different synthetic  … as part of the Community Science Program (CSP)  Functional Genomics proposal call. …
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Genome sequence of the moderately thermophilic sulfur-reducing bacterium Thermanaerovibrio velox type strain (Z-9701T) and emended description of the genus Thermanaerovibrio
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Who We Are
… of Energy (DOE) Joint Genome Institute (JGI) is a national user facility located at Lawrence Berkeley National Laboratory. The JGI consists of around 280 researchers and support staff in the Integrative Genomics Building in Berkeley, California.  Our location at …
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