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Boosting Small Molecule Production in Super “Soup”
Do metabolic pathways from engineered yeasts still work in cell-free environments? (Spoiler: Yes.) Think of cells as tiny factories: within their walls they have both the machinery to …
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Toward More Reproducible, Reusable Stable Isotope Probing Experiments
… with the prospect of meta-analyses boosted by AI and Machine Learning — JGI researchers and collaborators work to create FAIR datasets to maximize returns on … are active, and which microbes are eating what,  in the environment.  This distinction — between presence and …
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Doubling Down on Known Protein Families
Using a novel computational approach, researchers confirm … exploring a dark room with a flashlight, only able to clearly identify what falls within that single beam. When … these families. They divided the protein families up by environment and found only 7% of protein families were shared …
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The Expanding Universe of Methane Metabolisms in Archaea
Metagenome-assembled archaeal genomes provide new insights into an ancient metabolism. Methane is a greenhouse … presence of methanogens in nearly all types of anaerobic environments suggest the diversity of methane metabolisms is …
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Natural Prodcast Episode 7: Ben Shen
… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s … regular schedule for a while. Moving forward, I’m hoping to get a new one out every two weeks. This time, we’ve got a …
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How Filamentous Fungi Sense Food
Tracing gene regulatory networks in the model fungus  Neurospora crassa . The Science A team … of California, Berkeley used a multi-omics approach to reconstruct and model gene regulatory pathways used by …
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A Collaboration to Improve Plant Genome Annotations Across Species
To provide broad plant genomic capabilities, the DOE Joint Genome Institute works in partnership with the … and involves more than 17 research groups. The team set out to characterize the transcriptome – the complete set of RNA …
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Getting to the Bottom of Fungal Functions Across Earth’s Forests
… have leveraged data from the 1000 Fungal Genomes project to form new connections between fungal guilds, genes and … way to access much more information about fungi in these environments. “Now with these new tools — metatranscriptomics, … a bit like diversifying an investment portfolio. If a stress like wildfire or drought threatens some fungal …
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Dan Rokhsar
Genome Institute in 2000 as the founding Associate Director for Computational Genomics, and led the computational … assisting the adaptation of plants to changing environments. … AB in Physics, Princeton University, NJ MS in … IBM Watson Research Center, Yorktown Heights, NY … Publications … 2018 Marthella Foskett Brown Chair, …
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Picking Up Threads of Cotton Genomics
Analysis reveals cotton genome stability across global lineages . Come harvest … Science “The results described in this  Nature Genetics publication will facilitate deeper understanding of cotton … of DOE missions related to clean energy generation and environmental characterization and cleanup. The JGI provides …
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Axel Visel
Dr. Visel joined the DOE Joint Genome Institute in 2010. As the Deputy … Institute in Hanover, Germany, where he developed novel tools for large-scale in situ gene expression analysis in … Computational Biology , Nucleic Acids Research . Over 80 publications in peer-reviewed journals including Nature, …
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Ben Bowen
… discoveries, supporting the DOE’s Biological and Environmental Research user community in their bioenergy and … State University, Tempe, Chemical Engineering Post-doctoral positions – Arizona State University, Bioengineering & … Google Scholar. … Education … Awards and Honors … Selected Publications …
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