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… results from single cells. The Science Studying the  genomes of microorganisms is incredibly useful for … most species do not grow easily in the lab. To access the genomes of uncultured  microbes , scientists usually employ … extracting single cells and then amplifying their DNA for genome sequencing was no easy task. The traditional way of …

… energy and environmental challenges. In March 2008, the genome sequence of the forest fungus Laccaria bicolor was … a symbiotic relationship with the poplar, a JGI Flagship Genome and the first tree to have its genome sequenced. Having this first genome sequence of a …

Researchers at the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User … in environmental genomics by writing for the column Genome Watch in  Nature Reviews Microbiology .  The latest … consider regularly writing for the magazine’s column Genome Watch? The column appears in six issues of the …

… collaborated with the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User … Annotation Group. Many of these bacterial and archaeal genome sequences have been generated using techniques that … Repertoire in Actinobacteria Over the years more than 3,400 genomes have been sequenced from curated DSMZ isolates, for …

… included researchers at the U.S. Department of Energy Joint Genome Institute (JGI), a DOE Office of Science User … a team of researchers sought to disrupt every gene in the genome with CRISPR-Cas9 in order to interrogate each one’s … a pool of sgRNA sequences: six for every gene in the genome. The JGI  DNA Synthesis Science team synthesized …

… (Graphic: Neil Byers) The JGI launched the 1000 Fungal Genomes (1KFG) Project through a 2012 Community Science … State University led the effort to sequence 1000 fungal genomes to create two reference genomes for all fungi families — essentially, the foundation …

… from plants is the high cost and resource requirements of processing these sturdy materials, rumen microbes and their … essentially what makes them so powerful that they can process tough cell walls.  “The JGI was really leading the … coherent pieces called contigs — into genes and even into genomes — from these environmental samples,” said Matthias …

… in Streptomyces coelicolor . The Impact As an integrative genome science user facility, connecting genes to functions … is almost impossible, and the experimental process for doing so is laborious and complex. RIViT-seq technology simplifies this identification process. Multiple factors mediate transcription, including …

… help solve energy and environmental challenges.   The Human Genome Project began in 1990 when the U.S. Department of … studying Chromosome 5, which contains about 6% of the human genome . They discovered genes linked to conditions such as … Chromosome 19, which contains about 2% of the human genome. They were interested in genes involved in repair of …

… of that modified chemical in any environment. Organisms who process the modified compound will have heavier DNA or RNA, … cycle nitrogen and carbon, or how freshwater ecosystems process methane and organic matter.  However, to get all of … proposal calls to the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User …

This year the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User … Mentors: Jessen Bredeson & Albert Wu Project: “ Pangenome de Bruijn Graph Simplification ” Peter Nguyen : … of a multiplex genomic integration system for the selection of genes essential for specialized carbon …