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PhycoCosm Tutorial
Learn more about PhycoCosm, the largest interactive collection of … analysis tools developed by the Joint Genome Institute (JGI), a US Department of Energy Office of Science user facility at …
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The Expanding Universe of Methane Metabolisms in Archaea
… insights into an ancient metabolism. Methane is a greenhouse gas 20 times more potent than carbon dioxide. Billions … the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility, for publicly … involving methyl-coenzyme M reductase (MCR), the final step in methanogenesis, or MCR-like complexes, likely …
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Olpidium, The Key to the Origin of Terrestrial Fungi
… (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility, found that the fungus Olpidium is a link in … remained largely untouched until seven years later. In 2018, as members of the ZyGoLife consortium , my colleagues and I decided to re-visit the Olpidium genome data . Taking the …
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Better Genome Editing for Bioenergy
… of the genes in a lipid-prolific yeast. The Impact The team used this set of guide RNAs on  Yarrowia lipolytica to … at the U.S. Department of Energy Joint Genome Institute (JGI), a DOE Office of Science User Facility. Y. lipolytica … and choose only the most reliable sgRNAs for their final set. Tool in hand, the team was ready to test what …
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From Sample Shipments to Sequences – A Tour of the JGI’s Sequencing Pipeline
Every year, the JGI sequences around 35,000 samples — from plants, algae, bacteria, archaea, fungi, viruses — to support scientists around the world. Most of those … send their samples in from afar, without ever hearing much about the sequencing lab. So today, Chris Daum walks through …
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Exploring the Diversity of the American Prairie’s Switchgrass
A tall native plant of the North American prairie, switchgrass ( Panicum … dizzying diversity. So, a team of scientists made an ambitious plan to begin to link the plant’s varying traits — height, … The undertaking took shovels, trucks — and more than a decade.  …
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A Revamped Amplification Method that Enables Nearly Complete Single-Cell Genomes
Studying the  genomes of microorganisms is incredibly useful for understanding the microbiome of the earth, but … The U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at … the majority of the cell’s genome is missing from the final assembly. So while researchers are confident all the …
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Exploring Possibilities: 2022 JGI-UC Merced Interns
… have influenced their careers in science. Hear more about what they learned from working with their JGI mentors, … Foster Irina Birskis Barros and mentors Elle Barnes and Susannah Tringe Shari Larsen and mentor Robert M. Bowers … research poster. And I was able to present at the, um, final symposium at UC Merced  Daravuth Cheam: The biggest …
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An Age of CRAGE: Advances in Rapidly Engineering Non-model Bacteria
A group led by JGI scientists have made strides in improving and applying a … is central to our ability to offer host-engineering for our users,” says JGI Director Nigel Mouncey. Using CRAGE, JGI … for investigating plant-microbe interactions. A final recent advance in CRAGE is the addition of CRISPR …
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Ancient Algae Reveal Secrets of Plant Evolution
Research uncovers the genetic foundations that helped plants conquer land over 600 million years ago. The Science … to terrestrial life paves the way for innovations in sustainable agriculture and clean energy. These evolutionary … the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at …
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Toward More Reproducible, Reusable Stable Isotope Probing Experiments
… to maximize returns on these advances. Over the last two decades, Stable Isotope Probing (SIP) has opened vast … which microbes are present in a sample, to generate data about which organisms are active, and which microbes are … microbial ecosystems. These communities harbor tens of thousands of different organisms who all consume different …
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Len Pennacchio
Pennacchio joined the DOE Joint Genome Institute and has focused on applying state-of-the-art molecular methods to … … The Deputy of Genomic Technologies serves as the JGI’s primary point of contact for all High-Throughput Data … in Genome Biology & Technology (AGBT)” … Education … About the Deputy of Genomic Technologies … Selected …
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