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Better Genome Editing for Bioenergy
… part of CRISPR-Cas9 technology to enable improvements in microbial oil production. The Science CRISPR-Cas9 is a … and xylose — into fatty acids that could be used for renewable fuel. In fact, lipids can make up more than 90 … sgRNA would lead Cas9 to make a lethal double-strand DNA break, a dysfunctional sgRNA would be harmless. The team was …
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JGI User Executive Committee Expands
Six new members have been elected to the User Executive … at the Donald Danforth Plant Science Center, where his group focuses on interactions underlying plant adaptation in … efficiently degrade complex polymers that are not easy to break down, as well as developing synthetic biology tools …
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Researching and Solving Real-World Problems with the 2023 JGI-UC Merced Interns
Juan C. Villada, Ecology & Evolution of Self-Catalytic Introns across Earth’s Microbiomes Sonia Vargas and mentors … in a model green alga called Chlamydomonas reinhardtii. We’re using an attentive deep learning model called … Tyml and Dr. Frederik Schulz with the New Lineages of Life Group at JGI. And we’ve been working on isolating and …
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Sequence-based bioprospecting of myo-inositol oxygenase (Miox) reveals new homologues that increase glucaric acid production in Saccharomyces cerevisiae
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User Advisory Committees
All staff members of the US Department of Energy (DOE) Joint Genome Institute (JGI) commit to Lawrence Berkeley National …
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Climate Change Threatens Base of Polar Oceans’ Bountiful Food Webs
… photosynthetic algae. But human-induced climate change , a new study suggests, is displacing these important cold-water … Instead, they sharply delineated into two big geographical groups: those in colder, polar waters, and those in warmer, … The team found that the boundary, or biodiversity ‘break point,’ between these algal communities occurs in …
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SPRUCE-ing Up Science
A former JGI intern is now applying his internship lessons on … fine tune his approach. “I got a lot of that from Zhong.”   Publication: Carrell AA et al. Habitat-adapted microbial … mediate Sphagnum peatmoss resilience to warming . New Phytol. 2022 Jun;234(6):2111-2125. doi: …
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Dan Rokhsar
Dr. Rokhsar joined the DOE Joint Genome Institute in 2000 as the founding … He currently leads the JGI’s Computational Genomics group, and is past lead of the Eukaryotic Genome Program … IBM Watson Research Center, Yorktown Heights, NY … Publications … 2018 Marthella Foskett Brown Chair, …
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Inspiring STEM Careers Through a Hands-on Everglades Microbiome Study
Journal publication caps JGI pilot project with fledgling Florida … not sure we could even complete a full project. Every other group I contacted was happy to offer advice but declined to … “When I originally envisioned the project of the class, I knew that I wanted them to write a final paper that  could be …
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Who We Are
…   The U.S. Department of Energy (DOE) Joint Genome Institute (JGI) is a national user facility located …
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Nikos Kyrpides
Dr. Kyrpides joined the DOE Joint Genome Institute in 2004 to lead the … Research with an emphasis on Microbiome Data Science. His group is developing novel methods for enabling large-scale … Thousands of Small, Novel Genes. Cell. 178(5):1245-1259. Publications on Pubmed | Google Scholar … Thomson Reuters …
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Cultivation of novel Atribacterota from oil well provides new insight into their diversity, ecology, and evolution in anoxic, carbon-rich environments
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