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… which are filamentous viruses with small, single-stranded DNA genomes and a unique chronic infection cycle. “We’re not … water, and humans—around the world. By the numbers, the new approach detected inoviruses in 3,609 (6 percent) of the … of phage-bacterial coevolution and are also useful tools in CRISPR-Cas applications, but we are limited in our …

… associated proteins that can target single-stranded DNA (ssDNA). The discovery was made possible by mining the … Microbial Genomes and Microbiomes (IMG/M) suite of tools managed by the U.S. Department of Energy (DOE) Joint … from infecting viruses and phages. In the event of a new infection, the microbes use the genetic information …

… leveraged data from the 1000 Fungal Genomes project to form new connections between fungal guilds, genes and function. … RNA to understand gene expression, and developed new tools to map that soil RNA to fungal genomes.  The U.S. … who nominated species for sequencing and then sent DNA and RNA samples to JGI,” Grigoriev said. All of these …