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… tools to automate sequence design for assembly by Gibson, Yeast recombination and Golden Gate methods … gRNA-SeqRET … …

… … DAN UDWARY: Hey, everyone. I’ve got a great episode for you here today. We got the opportunity to talk to one of the real legends of … your origin story in natural products? How did you get started in this area? BILL FENICAL: Yeah, well, thank you, …

BARONA-GOMEZ: I think that the very first thing that got us into this is that we should, in any case, use … that a secondary metabolism as a field, or subdisciplines, started to grow and have different perspectives– from the … it’s not central because it’s not just supports energy and yeast-type function, it’s very specialized function, which …

… form. And so do you want to tell us a little bit about what got you into natural products and got you excited about the world of natural products? ALISON … promiscuity in the substrates it operates on. DAN UDWARY: Got it, OK, OK. JACKIE WINTER: So when you’re developing …

To engineer yeast to do more, and understand genomes in general, Jef … and Leslie Mitchell (Neochromosome) have worked to replace yeast’s native chromosomes with synthetic versions. This … the goal is to create an entirely human-generated yeast genome. …

… with, and I think you all will be too. But, today, I got the chance to work with my JGI colleague Menaka Wilhelm, … which users work with our facility to do science. Since I started working for JGI, and especially since I started the podcast, I get lots of questions from scientists …

Do metabolic pathways from engineered yeasts still work in cell-free environments? (Spoiler: Yes.) … describe a two-pronged approach that starts with engineered yeast cells but then moves out of the cell structure into a … products in industry.” From Cell to “Soup” The work started with yeast strains engineered by Alper’s team to …