Search

… intriguing. The squid – the Hawaiian bobtail squid has two organs that solely house– whose sole function is to … does some really exciting work there. And I thought, well, why don’t we try to go to Alaska and see what we can find … with any kind of gene cluster identification, doing it with sequence alone you have to have some kind of a template to …

… that got me into natural products to be truthful. So, well, two things. My PhD work was with a fungal pathogen called … out introns and dealing with, you know, weirdness in the sequence. You know, some clusters are not clustered…   … it so easily with fungi. So…   NANCY: Yeah, I don’t know why. For example, with that – actually there’s a good talk …

… then genomics happened. Dan: Yeah, I did my first genome sequence with you. Brad: That’s right,  Dan: JGI did it in … Sequencing Program, and they worked with us to sequence two genomes. Those were of Salinospora tropica and arenicola … working with you, Dan, on this one, and we said, “Well, why don’t we have you know, the bioinformaticians go against …

… learned a lot so much history from this conversation about why the ocean was basically unexplored until the 70s, and … today, run full-fledged marine chemical ecology programs. Two of the great students are in Georgia, in Atlanta, at … forward to seeing the data when it finally gets off the sequencers. The pandemic has obviously slowed JGI down a …

… and eukaryotic microbes and viruses in environmental sequence data. We use multi-omics (metagenomics, … on ecosystem function: We investigate the intricate networks of relationships between microbes and their hosts. … tool for generating synthetic sequencing data from genomic sequences …

… The  1000 Fungal Genomes Project is a five-year project to sequence 1000 fungal genomes from across the Fungal Tree of … of fungi. Mycocosm enables users to navigate across sequenced fungal genomes, and to conduct comparative and … resource hub that provides access to publicly available sequenced algal genomes and genome annotations generated by …

… of their synthases so that we can start to use the DNA sequence to predict or just understand better the language … your interest in getting into natural products. DAN: Why are you here at SIMB? AARON PURI: Yeah. Thanks Jackie. … scientific audience whereas now I’m sitting here with two people who know way more about natural products than I …

… the foundation for a large-scale CSP proposal submission. Sequence requests should not exceed 3 Tb in total. Proposals … of Intent are not required. Applicants may submit up to two proposals per year (but may be listed as co-PI on an unlimited number of proposals).  For accepted proposals, …

… mining, and how we might start to better connect those two things, because I think that’s ultimately what needs to … Apple Podcasts or wherever you’re getting this and tell me why you’re listening. DAN: But, now, here’s Natural Prodcast … And that’s been followed by developments in pulse sequences and improvements in the ways in which you acquire …

… stories about natural products, so you can get a feel for why I think they’re so important, and we’ll start to explain … more about some of the background and sort of the reasons why we want to do this. And also to provide a little more … of the fun things that I hope that I can express today is why secondary metabolism is interesting and why it is that …

… Our research focuses on the assembly of metagenomic sequence data into microbial genomes, which is of … As ANI provides a measure of genomic similarity between two genomes,  we use it to identify and classify bacteria … Profile HMM search across all IMG metagenomes, capturing sequence diversity for proteins of interest. …

… about Antarctica, and we want to talk about molecular networking, because I really enjoyed the review that you wrote … Duncan: Yeah. I love actinomycetes. Dan Udwary: Tell us why. I mean, I know, but I think– Alison Takemura: I want to … of almost finished characterizing them. We’ve got genome sequences, which are just incredible. We’ve looked at the …