Results
… and annotation of all publicly available genomes from three domains of life, in a uniquely integrated context. … … comprising the largest public collection of plasmid sequences identified from genomes, SAGs, MAGs, metagenomes …
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… interactions. The PDT enables industry engagement through three primary routes: … The CSP provides the scientific …
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… wear my prosthetic leg. I had my leg amputated when I was three and almost died of an infection following the … culture-disconnected. Like we’ll take some soil samples and sequence all the bugs out of that or whatever. And so I was … methicillin-resistant Staphylococcus aureus . Can you share why finding treatments for these microbes is so important? …
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… at JGI start with sequencing, but where else did those sequences go? Like, what are the other scientific tools we … that describe the work. In general. Scientific merit and why it’s important. The DOE mission is one of these … our process and we’ll have it off to you within 90 days. Three months. We offer 5 to 10 kb size synthesis. We offer …
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… is like, what’s your origin story in natural products? Why are you doing this? JACLYN WINTER: I’ll kind of go back … have an E. coli strain that we’ve been working on that we sequenced the genome. And it has 17 resistant genes on a … how to look at the different Frankia genomes. And we had three genomes. We did comparative analysis. We did structure …
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… about the basics of genome mining, which is using DNA sequence to identify and interpret biosynthetic, secondary … biological perspective, like what was this bacterium, and why did your group want to study it? Marnix Medema: You mean … bigger and better for eventually one of antiSMASH with the three of us, but unfortunately we didn’t know about that. …
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… and eukaryotic microbes and viruses in environmental sequence data. We use multi-omics (metagenomics, …
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… at genomes and seeing where the really hard things to sequence were, and wondering what those … what those were … functional was these secondary metabolite pathways. So why was that? What is it about secondary metabolite pathways … has developed a system. It’s relatively simple. So there’s three members, there’s a Bacillus , there’s a …
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… and environmental sustainability. Fungi, with million species, are essential for ecosystem functioning — … The 1000 Fungal Genomes Project is a five-year project to sequence 1000 fungal genomes from across the Fungal Tree of … of fungi. Mycocosm enables users to navigate across sequenced fungal genomes, and to conduct comparative and …
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… does some really exciting work there. And I thought, well, why don’t we try to go to Alaska and see what we can find … able to produce chemistry that deals with reactive oxygen species and so potentially could go down that route. DAN: … with any kind of gene cluster identification, doing it with sequence alone you have to have some kind of a template to …
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… in doing so enabled the JGI to be the first to publish the sequence analysis of the target chromosomes 5, 16, and 19, … to advance basic science by sequencing scores of microbial species as well as several model organisms and contributing … JGI that contribute to meeting this goal focus on one of three categories: terrestrial plants that can be used as …
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… is also reflected in the strongly biased representation of sequenced genomes in the public domain, the bulk of which belong to only three phyla. The Woyke group uses single-cell sequencing as …
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