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… stories about natural products, so you can get a feel for why I think they’re so important, and we’ll start to explain … more about some of the background and sort of the reasons why we want to do this. And also to provide a little more … of the fun things that I hope that I can express today is why secondary metabolism is interesting and why it is that …

… Proposals aim to sequence and annotate genomes from Antarctica to Africa to … interested in learning more about the fungal endophytes of soybean and how they deter two significant pathogens, the soybean cyst nematode and the soybean sudden death pathogen. In the …

… at JGI start with sequencing, but where else did those sequences go? Like, what are the other scientific tools we … that describe the work. In general. Scientific merit and why it’s important. The DOE mission is one of these … section. We want to be sure that the PIs can articulate why their work falls within one of these DOE mission areas. …

… The deliverables can range from raw sequence data to well-annotated assembled genomes to … listing of approved proposals can be found here. All sequence data will be accessible on the JGI Data Portal. … How much will it cost me to sequence or synthesize my target or obtain metabolomics data? …

… you maybe explain what’s going on with their biology and why they’re so important to natural products? ERIC:  Sure. … I’ve seen you give a few talks on that. Can you tell us why cone snails are so cool? ERIC:  So cone snails are … turns a peptide, for example, from a disordered sequence into an antibiotic that kills bacteria through a …

… And at the time, it was really exciting when people would sequence [DNA]. The genome was– well, that hadn’t really … polyketide synthase and then P3. We still don’t know why 20 years later. JACKIE WINTER: It’s pretty amazing, … And that’s what I really wanted to do. And that’s why I came back to academia. And I set that up. And we …

… We focus our efforts on integrating database mining and sequence design with scaling the production of large, … developing methods for converting digital information from sequence databases into biotechnological or environmental …

… I request a culture/slant/DNA of an organism that has been sequenced at the JGI? …

… is like, what’s your origin story in natural products? Why are you doing this? JACLYN WINTER: I’ll kind of go back … that I never anticipated starting– that’s not why I came to the University of Utah– is looking at the … have an E. coli strain that we’ve been working on that we sequenced the genome. And it has 17 resistant genes on a …

… then genomics happened. Dan: Yeah, I did my first genome sequence with you. Brad: That’s right,  Dan: JGI did it in … working with you, Dan, on this one, and we said, “Well, why don’t we have you know, the bioinformaticians go against … get made fun of by my now-wife, because she was wondering why it is that we needed to produce more toxins in the lab …