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… stories about natural products, so you can get a feel for why I think they’re so important, and we’ll start to explain … more about some of the background and sort of the reasons why we want to do this. And also to provide a little more … of the fun things that I hope that I can express today is why secondary metabolism is interesting and why it is that …

We focus our efforts on integrating database mining and sequence design with scaling the production of large, … developing methods for converting digital information from sequence databases into biotechnological or environmental …

… for advice!      … The deliverables can range from raw sequence data to well-annotated assembled genomes to … listing of approved proposals can be found here. All sequence data will be accessible on the JGI Data Portal.   … … the CSP and FICUS programs? … How much will it cost me to sequence or synthesize my target or obtain metabolomics …

… at JGI start with sequencing, but where else did those sequences go? Like, what are the other scientific tools we … that describe the work. In general. Scientific merit and why it’s important. The DOE mission is one of these … section. We want to be sure that the PIs can articulate why their work falls within one of these DOE mission areas. …

… and eukaryotic microbes and viruses in environmental sequence data. We use multi-omics (metagenomics, …

… through end-to-end automation, and further advancing sequence applications, single cell genomics, DNA synthesis, …

… tool BOOST , which provides a suite of tools to automate sequence design for assembly by Gibson, Yeast recombination …

… you maybe explain what’s going on with their biology and why they’re so important to natural products? ERIC:  Sure. … I’ve seen you give a few talks on that. Can you tell us why cone snails are so cool? ERIC:  So cone snails are … turns a peptide, for example, from a disordered sequence into an antibiotic that kills bacteria through a …

And at the time, it was really exciting when people would sequence [DNA]. The genome was– well, that hadn’t really … polyketide synthase and then P3. We still don’t know why 20 years later. JACKIE WINTER: It’s pretty amazing, … And that’s what I really wanted to do. And that’s why I came back to academia. And I set that up. And we …

… and Environmental Research (BER) program, set the final sequence allocation for this program. …

… comprising the largest public collection of plasmid sequences identified from genomes, SAGs, MAGs, metagenomes …