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… … For sequencing projects, once work is under way, raw sequence data is released to NCBI’s Sequence Read Archive on a regular basis, in accordance with …

… capabilities and products . A minimum request of 1 Tb of sequence data is required to qualify for BERSS. For DNA … and personnel resources for genomic research and sequence-based science.  Projects include de novo generation … of genome data, assistance in interpreting and/or building on an existing data set, or the refining of new …

The JGI mural on the 3rd floor of the Integrative Genomics Building whimsically references dozens of iconic JGI …

… of their synthases so that we can start to use the DNA sequence to predict or just understand better the language … your interest in getting into natural products. DAN: Why are you here at SIMB? AARON PURI: Yeah. Thanks Jackie. … chemical biology, a lot of which people classify as tool building. So I worked with a really great guy named Matt …

… genomics. The two-story mural at the Integrative Genomics Building was painted by Berkeley-based artist Nigel Sussman …

… the paradigm of how to discover natural products. So, why I’m very excited to be working with Dan, you, with the … develop enabling technologies. ie how to translate the ATGC sequence into discrete small molecules. So, Dan, I’m very … or you know, you’ve run into challenges that demonstrate why this is so important. BEN:  Yeah. So I wouldn’t call it …

… storage during simulated range shifts of plant-fungal symbionts … Elucidation of the gene regulatory networks …

… at JGI start with sequencing, but where else did those sequences go? Like, what are the other scientific tools we … that describe the work. In general. Scientific merit and why it’s important. The DOE mission is one of these … section. We want to be sure that the PIs can articulate why their work falls within one of these DOE mission areas. …

… about the basics of genome mining, which is using DNA sequence to identify and interpret biosynthetic, secondary … biological perspective, like what was this bacterium, and why did your group want to study it? Marnix Medema: You mean … had to scale also by orders of magnitude. And that’s why Satria figured out some new clever tricks to make an …

… computational analyses of BGC size and complexity, BGC sequence composition, metabolic similarity & compatibility, … of horizontal gene transfer. … The SMC provides complete sequence and annotation data for secondary metabolite … and the public, and provide programmatic access to all sequence and annotation data and their comments. … JGI …

… is like, what’s your origin story in natural products? Why are you doing this? JACLYN WINTER: I’ll kind of go back … have an E. coli strain that we’ve been working on that we sequenced the genome. And it has 17 resistant genes on a … none of that is going to change. It’s only just– we’re just building onto it. So the site is usable now. The website is …

… comprising the largest public collection of plasmid sequences identified from genomes, SAGs, MAGs, metagenomes …