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… studied chemistry, because she switched her degree program from geography to chemistry. So we were both enrolled as … Duncan: Yeah. I love actinomycetes. Dan Udwary: Tell us why. I mean, I know, but I think– Alison Takemura: I want to … of almost finished characterizing them. We’ve got genome sequences, which are just incredible. We’ve looked at the …

… over our interview with Dr Elizabeth (or Betsy) Parkinson from Purdue University. She’s in the Department of Chemistry … The genes are pretty much 100% identical. We don't know why one is expressed over the other. As far as whether we're … usually serve as dimers, and then they will bind to certain sequences of DNA. And when they bind to those certain …

DAN: Welcome back to Natural Prodcast! This is episode 4! From here on out, for a while, we’re going to be presenting … out introns and dealing with, you know, weirdness in the sequence. You know, some clusters are not clustered…   … it so easily with fungi. So…   NANCY: Yeah, I don’t know why. For example, with that – actually there’s a good talk …

… about the basics of genome mining, which is using DNA sequence to identify and interpret biosynthetic, secondary … we get to present our conversation with Marnix Medema , from Wageningen University in the Netherlands. Marnix is … biological perspective, like what was this bacterium, and why did your group want to study it? Marnix Medema: You mean …

… and delays on the work. The transfer of a proposal from one commercial institution to a new commercial … Before work can begin on proposals submitted by researchers from another DOE National Laboratory, a JGI-BDLUA ,  BDLUA … multiple collaborator proposals submitted by researchers from another Federal Agency, all collaborating institutions …

… capabilities support researchers exploring how to convert sequence into functional assessments. This is done by … platform enables users to validate hypotheses generated from mining genomic data by designing and assembling … design tool  … BOOST provides a suite of tools to automate sequence design for assembly by Gibson, Yeast recombination …

Laboratory. Being a User Facility means that scientists from all over the world bring us big problems related to … stories about natural products, so you can get a feel for why I think they’re so important, and we’ll start to explain … near this tree and so there was probably some historical evolutionary event where the DNA transferred from the fungus …

Prodcast. This week, Alison and I talk to Roger Linington, from Simon Fraser University in British Columbia, Canada. … Apple Podcasts or wherever you’re getting this and tell me why you’re listening. DAN: But, now, here’s Natural Prodcast … And that’s been followed by developments in pulse sequences and improvements in the ways in which you acquire …

… are open to both domestic and international applicants from any institution type and at any career stage. … for advice!      … The deliverables can range from raw sequence data to well-annotated assembled genomes to … listing of approved proposals can be found here. All sequence data will be accessible on the JGI Data Portal.   … …

… the University of Hawaii and moved there in the early ’60s from Berkeley to work on this new budding field of marine … then genomics happened. Dan: Yeah, I did my first genome sequence with you. Brad: That’s right,  Dan: JGI did it in … working with you, Dan, on this one, and we said, “Well, why don’t we have you know, the bioinformaticians go against …

… that there wasn’t enough application there. And so I moved from there to plant natural products, getting a PhD in … does some really exciting work there. And I thought, well, why don’t we try to go to Alaska and see what we can find … with any kind of gene cluster identification, doing it with sequence alone you have to have some kind of a template to …