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… conversation with Aaron Puri. He is an Assistant Professor from the Chemistry department at the University of Utah, so … of their synthases so that we can start to use the DNA sequence to predict or just understand better the language … your interest in getting into natural products. DAN: Why are you here at SIMB? AARON PURI: Yeah. Thanks Jackie. …

… JGI serves more than 2,500 users that predominately come from the public sector: academic and government institutions … Our metabolomics platform delivers rich metabolite profiles from diverse biological and environmental samples by using … our User Program’s Community Science Program, the JGI sequenced and characterized 270 genomes of the Clostridium …

… studied chemistry, because she switched her degree program from geography to chemistry. So we were both enrolled as … Duncan: Yeah. I love actinomycetes. Dan Udwary: Tell us why. I mean, I know, but I think– Alison Takemura: I want to … of almost finished characterizing them. We’ve got genome sequences, which are just incredible. We’ve looked at the …

… about the basics of genome mining, which is using DNA sequence to identify and interpret biosynthetic, secondary … we get to present our conversation with Marnix Medema , from Wageningen University in the Netherlands. Marnix is … biological perspective, like what was this bacterium, and why did your group want to study it? Marnix Medema: You mean …

… and delays on the work. The transfer of a proposal from one commercial institution to a new commercial … Before work can begin on proposals submitted by researchers from another DOE National Laboratory, a JGI-BDLUA ,  BDLUA … multiple collaborator proposals submitted by researchers from another Federal Agency, all collaborating institutions …

… Laboratory. Being a User Facility means that scientists from all over the world bring us big problems related to … stories about natural products, so you can get a feel for why I think they’re so important, and we’ll start to explain … near this tree and so there was probably some historical evolutionary event where the DNA transferred from the fungus …

… the University of Hawaii and moved there in the early ’60s from Berkeley to work on this new budding field of marine … then genomics happened. Dan: Yeah, I did my first genome sequence with you. Brad: That’s right,  Dan: JGI did it in … working with you, Dan, on this one, and we said, “Well, why don’t we have you know, the bioinformaticians go against …

… Prodcast. This week, Alison and I talk to Roger Linington, from Simon Fraser University in British Columbia, Canada. … Apple Podcasts or wherever you’re getting this and tell me why you’re listening. DAN: But, now, here’s Natural Prodcast … And that’s been followed by developments in pulse sequences and improvements in the ways in which you acquire …

… are open to both domestic and international applicants from any institution type and at any career stage. … users are able to work with Berkeley Lab.  However, users from certain countries (Iran, North Korea, Cuba, and Syria), need DOE permission and authorization from other U.S. government agencies to work with Berkeley …

… at improving our collective understanding of ecological and evolutionary parameters driving virus:host dynamics in … of phage and virus genomes have been assembled and reported from metagenomes, our understanding of the impacts of these … to identify, filter, cluster, annotate, and bin viruses from metagenomes. mSystems 9:e00888-24. …

… approaches to identify and characterize genomic information from uncultivated microbes and viruses. We develop … Our research focuses on the assembly of metagenomic sequence data into microbial genomes, which is of … potential applications. By recovering population genomes from metagenomes, we gain insights into microbial …