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… say a clutch is probably the size of a golf ball and has 25 to 50 eggs. I’m guessing here.  DAN: Sure, sure.  MARCY: … does some really exciting work there. And I thought, well, why don’t we try to go to Alaska and see what we can find … with any kind of gene cluster identification, doing it with sequence alone you have to have some kind of a template to …

… and eukaryotic microbes and viruses in environmental sequence data. We use multi-omics (metagenomics, … available at Google Scholar. Schulz, C Abergel, T Woyke (2022) Giant virus biology and diversity in the era of …

… is like, what’s your origin story in natural products? Why are you doing this? JACLYN WINTER: I’ll kind of go back … in this hypersaline environment, which can range from 8% to 28% salinity. We have toxic metals, so these concentrations … have an E. coli strain that we’ve been working on that we sequenced the genome. And it has 17 resistant genes on a …

… through end-to-end automation, and further advancing sequence applications, single cell genomics, DNA synthesis, …

… you maybe explain what’s going on with their biology and why they’re so important to natural products? ERIC:  Sure. … I’ve seen you give a few talks on that. Can you tell us why cone snails are so cool? ERIC:  So cone snails are … turns a peptide, for example, from a disordered sequence into an antibiotic that kills bacteria through a …

… tool BOOST , which provides a suite of tools to automate sequence design for assembly by Gibson, Yeast recombination …

… manipulation in the laboratory. Both germplasm (sequenced mutants and natural accessions) and protocols …

… learned a lot so much history from this conversation about why the ocean was basically unexplored until the 70s, and … seems hard to believe in retrospect. BILL FENICAL: Well, in 2021, absolutely hard to believe. But when you go way back, … forward to seeing the data when it finally gets off the sequencers. The pandemic has obviously slowed JGI down a …

… and Environmental Research (BER) program, set the final sequence allocation for this program. …