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Data from marine heatwave event may foreshadow climate change impact on … predictive models on how climate change may impact marine microbes and by extension, the ocean’s capacity to act as a … samples. Genomic DNA extracted from the water samples were sequenced by the U.S. Department of Energy (DOE) Joint …

A deep dive into microbial genomics reveals one bacterial species is … In the ocean’s North Pacific Subtropical Gyre, microbes tend to stay localized at different depths. But … of SAR324 cells and their gene expression, the team then sequenced community genomes and expressed gene transcripts …

… use natural products necessarily. Fungi are large. They’re microbes, but they’re large microbes. And they have all … out introns and dealing with, you know, weirdness in the sequence. You know, some clusters are not clustered…   … it so easily with fungi. So…   NANCY: Yeah, I don’t know why. For example, with that – actually there’s a good talk …

Program works to uncover the roles of small molecules in biological systems, linking them with genomic data to … processes, development of high performance plants and microbes, and understanding microbiome interactions. The  … insights into how small molecules function within plants, microbes, and ecosystems. Identifying and analyzing primary …

… of their synthases so that we can start to use the DNA sequence to predict or just understand better the language … your interest in getting into natural products. DAN: Why are you here at SIMB? AARON PURI: Yeah. Thanks Jackie. … ecology community to be able to better predict how their microbes are interacting with each other from sequence …

The Joint Genome Institute's DNA Synthesis Platform capabilities support researchers exploring how to convert sequence into functional assessments. This is done by … design tool  … BOOST provides a suite of tools to automate sequence design for assembly by Gibson, Yeast recombination …

… at genomes and seeing where the really hard things to sequence were, and wondering what those … what those were … was looking to develop new methods for DNA sequencing of microbes. And what kept breaking our methods was these damn … functional was these secondary metabolite pathways. So why was that? What is it about secondary metabolite pathways …

… activity. So the chemistry and function really of those microbes that live there.  And in our work we’ve determined … does some really exciting work there. And I thought, well, why don’t we try to go to Alaska and see what we can find … with any kind of gene cluster identification, doing it with sequence alone you have to have some kind of a template to …

… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s … the paradigm of how to discover natural products. So, why I’m very excited to be working with Dan, you, with the … develop enabling technologies. ie how to translate the ATGC sequence into discrete small molecules. So, Dan, I’m very …

Kerrie Barry or Vivian Ng Prokaryotic projects: Tijana Glavina del Rio , Danielle Graham , or Miranda Harmon-Smith DNA … be accessed via the Genome Portal , at the following sites: Microbes: IMG (citation: https://doi.org/10.1093/nar/gkaa939 … I request a culture/slant/DNA of an organism that has been sequenced at the JGI? … How do I check the current status of …

… … DAN: You’re listening to the US Department of Energy Joint Genome Institute’s … able to explore DNA sequencing and actually get to the DNA sequence – sequences for the genes that code for the … Something that’s you know …  ALISON: Central! DAN: That’s why they called it that! But for, maybe, people who are less …