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… at genomes and seeing where the really hard things to sequence were, and wondering what those … what those were … was looking to develop new methods for DNA sequencing of microbes. And what kept breaking our methods was these damn … functional was these secondary metabolite pathways. So why was that? What is it about secondary metabolite pathways …

DNA Synthesis Program supports a wide range of projects, from single-gene synthesis to the synthesis of entire … Program aims to generate large datasets to explore sequence-function relationships, advancing the discovery of … vision for a sustainable, bio-based economy. … Genome to Enzymes and Pathways focuses on discovering and …

…     Our homepage video includes external footage from:  University of Delaware Laura.Selbmann©PNRA. All the … in doing so enabled the JGI to be the first to publish the sequence analysis of the target chromosomes 5, 16, and 19, … Science Program, characterize organisms (plants and microbes) relevant to the DOE science mission areas of …

… activity. So the chemistry and function really of those microbes that live there.  And in our work we’ve determined … does some really exciting work there. And I thought, well, why don’t we try to go to Alaska and see what we can find … with any kind of gene cluster identification, doing it with sequence alone you have to have some kind of a template to …

… to identify over 27,000 microbial genes. The data from that study is now used across California State … of a course-based undergraduate resource experience. Hear from CSU San Marcos Professor Matt Escobar and UC Davis … of the JGI User Executive Committee, on how that study went from the lab to the classroom. …

… learned a lot so much history from this conversation about why the ocean was basically unexplored until the 70s, and … you think about the fact that, when plants and animals and microbes evolve, they evolve to make molecules that improve … forward to seeing the data when it finally gets off the sequencers. The pandemic has obviously slowed JGI down a …

… processes, development of high performance plants and microbes, and understanding microbiome interactions. The  … mass spectrometry-based methods to analyze metabolites from a wide range of biological and environmental samples — … communities, and samples including state-of-the-art instrumentation and informatic approaches.By bridging genomics …

… of novel bacterial, archaeal and eukaryotic microbes and viruses in environmental sequence data. We use multi-omics (metagenomics, …

… what’s important in terms of the chemistry produced by microbes. And by what’s important, I mean, like, where … Duncan: Yeah. I love actinomycetes. Dan Udwary: Tell us why. I mean, I know, but I think– Alison Takemura: I want to … of almost finished characterizing them. We’ve got genome sequences, which are just incredible. We’ve looked at the …

… at JGI start with sequencing, but where else did those sequences go? Like, what are the other scientific tools we … where smaller proposals may be a fit. Still not 20 many microbes. We still we work in plates, right? We’re a high … that describe the work. In general. Scientific merit and why it’s important. The DOE mission is one of these …