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… joined the JGI in 2017, he brought with him 20 years of industry experience — and an opportunity to expand the … computer analysis coupled with liquid chromatography mass spectrometry. We offer accessible, AI-ready large-scale data repositories for genome information with analysis tools for mining and …

… The mission of the Joint Genome Institute is to serve the scientific … relevant bioenergy and environmental problems.  The mission of the National Energy Research Scientific Computing Center … and readiness to begin work, checking such factors as genome size, polymorphism level, sample quality and …

… DAN: Hello, everyone, and Welcome back for Episode 14 of Natural Prodcast . There’s been a lot going on, so I took … off today with my interview with the Director of the Joint Genome Institute and head of the Secondary Metabolites … to some people more about down the road. Email Nigel! He’ll sequence whatever you want!  [LAUGHTER]  NIGEL MOUNCEY: We …

… Data produced and released by the US Department of Energy (DOE) Joint Genome Institute (JGI) are subject to the following Data … FY22 and later through the Community Science Program (CSP), Facilities Integrating Collaborations for User Science … is granted to proposal PIs, Co-PIs, and collaborators of any given proposal. Third parties (often referred to as …

… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a … stories about natural products, so you can get a feel for why I think they’re so important, and we’ll start to explain … a podcast produced by the US Department of Energy Joint Genome Institute. In each episode, we’ll be discussing the …

… enzymes to do chemical reactions. Obviously, in my work, in genome mining, we have an awful lot of crossover, where us … enzymes are, right? ALISON NARAYAN: Yes, and so that’s why I don’t like that sentence. I think that sometimes, we … association that might help? Like, if you have an unknown sequence or new flavin monooxygenases, you could say, oh …

… does some really exciting work there. And I thought, well, why don’t we try to go to Alaska and see what we can find … almost never Actinomycetes. And so when we look at their genomes we don’t get the same kind of information that we … with any kind of gene cluster identification, doing it with sequence alone you have to have some kind of a template to …

… expertise and infrastructure enable a broad community of scientists and engineers to leverage our data to develop new algorithms, models and tools in support of DOE mission priorities. Data discoverability and … the JGI will move to a new login service, requiring the use of an ORCID account with two-factor authentication enabled …

… exposure to working with Streptomyces, learning more about genome mining, as well as isolation and a little bit of … The genes are pretty much 100% identical. We don't know why one is expressed over the other. As far as whether we're … usually serve as dimers, and then they will bind to certain sequences of DNA. And when they bind to those certain …

… is like, what’s your origin story in natural products? Why are you doing this? JACLYN WINTER: I’ll kind of go back … Breaking Bad, I guess. But no, you trained me in how to genome mine, so thank you for that. And you had to put up … have an E. coli strain that we’ve been working on that we sequenced the genome. And it has 17 resistant genes on a …

… DAN: You’re listening to the US Department of Energy Joint Genome Institute’s “Natural Prodcast,” a podcast about the … you maybe explain what’s going on with their biology and why they’re so important to natural products? ERIC:  Sure. … turns a peptide, for example, from a disordered sequence into an antibiotic that kills bacteria through a …