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… … Dan Udwary: You’re listening to the Department of Energy … about the basics of genome mining, which is using DNA sequence to identify and interpret biosynthetic, secondary … biological perspective, like what was this bacterium, and why did your group want to study it? Marnix Medema: You mean …

… … DAN UDWARY: Hey everyone and welcome back to a new session of … And at the time, it was really exciting when people would sequence [DNA]. The genome was– well, that hadn’t really … polyketide synthase and then P3. We still don’t know why 20 years later. JACKIE WINTER: It’s pretty amazing, …

… … DAN: Welcome back for episode 9 of Natural Prodcast. This … Apple Podcasts or wherever you’re getting this and tell me why you’re listening. DAN: But, now, here’s Natural Prodcast … And that’s been followed by developments in pulse sequences and improvements in the ways in which you acquire …

With collaborative user projects, the JGI’s Plant Program delves into … computational framework. It enables cross-species comparisons, advancing DOE mission-oriented research and … manipulation in the laboratory. Both germplasm (sequenced mutants and natural accessions) and protocols …

…   The U.S. Department of Energy (DOE) Joint Genome Institute (JGI) is a national user facility located at Lawrence Berkeley …

…   The JGI’s Secondary Metabolites Program focuses on the exploration of secondary metabolites across bacteria, fungi, algae and … computational analyses of BGC size and complexity, BGC sequence composition, metabolic similarity & compatibility, …

… … Dan Udwary: Hey, Alison Takemura: Hey, Dan. Dan Udwary: Today … Duncan: Yeah. I love actinomycetes. Dan Udwary: Tell us why. I mean, I know, but I think– Alison Takemura: I want to … of almost finished characterizing them. We’ve got genome sequences, which are just incredible. We’ve looked at the …

The mission of the Joint Genome Institute is to serve the scientific community as a user facility pioneering functional genomics to solve … … For sequencing projects, once work is under way, raw sequence data is released to NCBI’s Sequence Read Archive on …

… … DAN: Hey, everybody. Welcome back for another episode of … of their synthases so that we can start to use the DNA sequence to predict or just understand better the language … your interest in getting into natural products. DAN: Why are you here at SIMB? AARON PURI: Yeah. Thanks Jackie. …

… … DAN: All right. Welcome back to Natural Prodcast. I did it. … The genes are pretty much 100% identical. We don't know why one is expressed over the other. As far as whether we're … usually serve as dimers, and then they will bind to certain sequences of DNA. And when they bind to those certain …

… … DAN: You’re listening to the US Department of Energy Joint … then genomics happened. Dan: Yeah, I did my first genome sequence with you. Brad: That’s right,  Dan: JGI did it in … working with you, Dan, on this one, and we said, “Well, why don’t we have you know, the bioinformaticians go against …

… … DAN: You’re listening to the US Department of Energy Joint … out introns and dealing with, you know, weirdness in the sequence. You know, some clusters are not clustered…   … it so easily with fungi. So…   NANCY: Yeah, I don’t know why. For example, with that – actually there’s a good talk …