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… and take soil and discover a new important drug from the microbes in that soil, there are now international … book you mentioned working on several antibiotic resistant microbes including a bacterium called methicillin-resistant … aureus . Can you share why finding treatments for these microbes is so important? CASSANDRA QUAVE: Yeah, that’s a …

… turned out to be a mixture of genetic material with various origins, ranging from fungi, plants to bacteria. Back in … for binning metagenome data involved with mainly eukaryotic origins were scarce. Thus, the genome and transcriptome data …

… And so that’s a big collection of natural product-producing organisms that Pfizer, you know, mined for years … microorganisms, the very first one for the natural product producing organism, the Actinomyces, was completed in early …

… you think about the fact that, when plants and animals and microbes evolve, they evolve to make molecules that improve … So around 1985, I said, why aren’t we studying microbes in the ocean? Why don’t we do that? DAN UDWARY: … animal to develop a drug was really difficult, working with microbes to develop a drug was not difficult at all. And …

… advanced sequencing technologies to decode the genomes of microbes in their natural environments. This work … and many other applications. By understanding how microbes contribute to ecosystem functions, the Program …

… try and increase titer and rate and drive down the cost of producing riboflavin at scale.  DAN: Got it.  NIGEL MOUNCEY: … But they really span our core science programs which are microbes, and fungi, and algae plants, synthetic biology. …

… what’s important in terms of the chemistry produced by microbes. And by what’s important, I mean, like, where … tools, in terms of looking at the chemistry produced by microbes, they’re pretty adaptable to other organisms. And … also produce natural products that can be helpful in producing biofuels? Because you had mentioned this …

… and dynamic metabolite networks of environmental microbes and how they transform their environment. Research …

… was looking to develop new methods for DNA sequencing of microbes. And what kept breaking our methods was these damn … so go check it out – but basically tied how the antibiotic producing bacteria on the ants related geography and … and deal with it is through these antibiotic- or antifungal-producing bacteria that live on the exoskeleton of the ants. …