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Declines in ice cover are accompanied by light limitation responses and community change in freshwater diatoms
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Frequently Asked Questions: Proposal Submission
… can range from raw sequence data to well-annotated assembled genomes to synthesized DNA constructs to … metabolomics data, depending on the specific product types covered in the call.    If you have technical questions, we … Utilization or transfer of any genetic resource may be covered by local, national or international regulation.  …
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Natural Prodcast Episode 7: Ben Shen
… of a natural product molecule around that. That’s sort of a semi-stable configuration of electrons that becomes really … right? BEN: Yeah, yeah. Well, we are at [10 to the] minus 12 [Molar concentration]- is sufficient to kill cells. So … will open up a new year for targeted anti cancer drug discovery. DAN: Yeah, great. Are any of these antibody-drug …
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Natural Prodcast Episode 24: Jackie Winter and SMC
… in this hypersaline environment, which can range from 8% to 28% salinity. We have toxic metals, so these concentrations … natural products, and especially if you’re in the drug discovery angle, is to look in industry. But you’re a … in the ’50s and ’60s of the golden age of antibiotic discoveries. Everything that we’re finding seems to be a new …
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User Support
… Notice Effective July 27, 2026, the JGI will move to a new login service, … IMG , GOLD and others for data annotation and submission Tracking, monitoring and expediting laboratory processing …
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Natural Prodcast Episode 10: A Primer on Genome Mining
… been the main driver for secondary metabolism drug discovery. Because we always need new antibiotics. We need new … Catalog of Earth’s Microbiomes. Nature  Biotechnology . 2020 Nov 9. doi: 10.1038/s41587-020-0718-6) DAN UDWARY: Yeah, … Genomes, or MAGs. So these are genomes that were assembled from metagenomic sequence, metagenomic sequence …
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Natural Prodcast Episode 14: Nigel Mouncey
… spinoza . And the other is spinetoram which is a semi-synthetic derivative of an intermediate in the spinosyn … new strains and new process improvements and new ways to recover spinosyns. And so we had a high throughput screening platform where we’d look at 10,000, 15,000, 20,000 mutants a week. We started doing a whole bunch of …
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Natural Prodcast Episode 2: The Primer, Part 2
… to the second episode of the Natural Prodcast. This is part 2 of our “primer” episode, so if you ended up here somehow … a little bit more giving. DAN: Alright, so I think we’ve covered a little bit about why they’re important. But one of … has been … not dominated by, but driven by drug discovery. We know that many natural product molecules are …
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New Lineages of Life Group
… Our research is focused on the discovery and characterization of novel bacterial, archaeal and … viral complexity and evolution Our research focuses on discovering and characterizing giant viruses, which possess … analyze large-scale biological datasets. This work helps uncover patterns and relationships in complex genomic and …
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Igor Grigoriev
… Dr. Grigoriev joined the JGI in 2003, following his postdoctoral training at UC Berkeley and … of diverse eukaryotic genomes, from protists to plants. In 2009, he launched the JGI Fungal Genomics program which resulted in over 2500 fungal genomes in the JGI MycoCosm portal. In 2018, he …
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Biodesign
… : a user science group dedicated to user project design, assembly, and quality control Strain Engineering Group : a … workflow management and novel automations for DNA design, assembly and analysis Overview of biodesign products The JGI … generated from mining genomic data by designing and assembling physical DNA constructs that can then be …
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Mining New Frontiers: The Critical Minerals and Materials Joint Call
… integrate genomics with nanoscale science, accelerating discoveries and developing transformative bio-based … technologies that address challenges in the sourcing, recovery, and utilization of critical minerals and materials. The proposal submission deadline is March 31, 2026 .  …
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