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… be proposing a larger project that requires the work of two or more DOE user science facilities. That’s kind of out … of the topics we cover. OK. Long intro today. We’ll have two discussions. First up is Tanja Woyke , JGI’s Deputy of … our eukaryotic genomes, all our eukaryotic genomes. Fungal plant, algal genomes, a lot of effort goes into generating …

… ag[riculture] and I really liked – I became interested in plant disease in part because of what happened in my Peace … that got me into natural products to be truthful. So, well, two things. My PhD work was with a fungal pathogen called … So it’s maybe the culture. I’m a faculty member in two departments at [the University of Wisconsin-Madison] UW. …

… of our Community Science Program, characterize organisms (plants and microbes) relevant to the DOE science mission … technologies needed to design, build, and control plants and microbes to produce biofuels, … and provide opportunities for biologically-based mitigation strategies. The JGI seeks to support projects that will …

… to do an independent study on ethnobotany of some of the plants that people were using for medicines in this very … intriguing. The squid – the Hawaiian bobtail squid has two organs that solely house– whose sole function is to … the glaciers and had this custom drill made to drill about two feet of glacier core that we field sterilized and …

… chemicals that are coming out of organisms, whether it be a plant or from the bottom of the ocean, from a sponge, or a … Sequencing Program, and they worked with us to sequence two genomes. Those were of Salinospora tropica and arenicola … special was like, you know, at that time, there are only two sequenced genomes of a Streptomyces , or gram-positive …

To provide broad plant genomic capabilities, the DOE Joint Genome Institute … Institute for Biotechnology, which specializes in genome improvement for plants. As part of that partnership, the JGI … resource. To demonstrate that, we included datasets from two species, one of which is sweet sorghum Rio from a JGI …

… of energy and nutrient exchange, as well as microbial and plant responses to environmental changes. With advanced mass … and their hosts on ecosystems.   Environmental molecular network:   ENVnet   is a comprehensive, mass spectrometry-based molecular network of metabolites designed to demystify the complexity of …

… scientific audience whereas now I’m sitting here with two people who know way more about natural products than I … so that’s weird, because it’s a bastardized version of the two because we’ll say methyl so we call them methylotrophs [ … DAN: Almost like you know that there is. AARON PURI: It’s a planted question Dan. Yeah. So overall I think what we’re …

Uncovering associations between plant roots and fungi that can help or harm plant host health. The Science Researchers compared the … colonize Arabidopsis thaliana roots with genomes from other plant-associated fungi. Their analysis identified fungal …

As a host, and a little bit of my newer work is focused on plants, but in both cases, you know, these molecules are how … sending signals. But really unpacking that complicated network of chemistry and communication is what I’m really … are … surrounding Tiny Earth is to create a course and a network of people to crowd-source antibiotic discovery. So …

… welcome back to a new session of Natural Prodcast. I’ve got two things I wanted to tell you about in this introduction. … not know what I was doing. BRIAN BACHMANN: Yeah, that makes two of us. DAN UDWARY: So the audio quality was terrible. … We can also genetically manipulate them. We can do strain improvements. We can do all sorts of things. So that’s just …

… so they’re secondary metabolite peptides. And there are two ways that nature does this. The more well-known … being a chemist, and it’s actually quite hard to put those two things together. And natural products is one of those … transcriptomics, metabolomics, and natural products in plants, fungi, and microorganisms. If you want to …