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… been involved with the AntiSMASH and MIBiG projects. And I found her review in natural product reports on the evolution … of it. So it wasn’t only chemistry or only biochemistry or genetics. It was also ecology. It was also evolution. It was … I could see a certain time span within these biosynthetic gene clusters. There’s gene fusion going on, and then I …
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… long. Well, when we went looking for a photo of John, we found one from the 70s in the Scripps library, and in it … see as the overall “theme” of your research? I know you’ve generally worked in various marine organisms. Except during … really need to know how they’re made. You need to bring the genes into the lab, and you need to manipulate them in the …
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… the National Institutes of Health and the National Science Foundation to create international partnerships in … America brought to the UK? ROGER: Yeah, it’s difficult to generalize, of course, but I felt overall that the British … my perspective, JGI has a large database of biosynthetic gene clusters and biosynthetic gene cluster fragments, and …
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… that can’t live without their host. They have no extra genes hanging around, they still dedicate 20-30% of their … of many different things in microbiology and biology in general. And her efforts first at Yale and now at University … that people were looking for in the soil kept getting found over and over again. So we call this the “rediscovery …
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… I was imagining some massive contraption for amplifying genes. I wasn’t really sure what actinobacteria were. Dan … currently exist. We looked at chemistry, so it’s really novel. And they’re just really exciting. And it really kind … new chemistry. If we want to stop finding stuff that we’ve found, or finding stuff that’s similar to things that we …
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… energy and ecosystem management. The program aims to generate high-quality genomic datasets, particularly for … single cell approaches. This includes linking strain-level genetic variation to ecological niche adaptations. Single … in particular to study inter-organismal interactions. Novel approaches are being explored to predict microbial …
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… Genomic science lies at the heart of biology, providing the foundational knowledge to understand, predict, and design … in advancing this frontier by supporting the scientific foundations that drive biotechnology and biomanufacturing … of biological processes that enable cost-effective energy generation and innovative materials production. Through …
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… genomics existed. This is before we’re even thinking of genes and connecting genes to molecules, which is something … like this pathway encodes a polyene chemical”. And they found one, and they solved a chemical structure. But they, … And perhaps using biocatalysts we can do it in a cleaner, greener way. That’s one of our motivations, as well. Alison: …
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… event that occured some 60 million years ago. Massive gene loss, rampant gene duplications, and even more ancient … history of a pivotal plant as well as the evolution of seed plants, the fern’s distant cousin. Ceratopteris … to have demonstrated the potential of ferns as sources of novel genetic material with applications including …
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… Center), HudsonAlpha and the JGI also identified a gene related to seed dispersal in wild populations for the first time. A 2020 …
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… Biotechnology. The work also led researchers to identify a gene related to seed dispersal in wild populations for the first time. I-Min Chen … genomics in support of DOE missions related to clean energy generation and environmental characterization and cleanup. …
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… I think for Natural Prodcast, I think the question that generally comes up that people come to me asking like is– … to end. So, we’ll talk about project requirements, expectations on the users end, on the JGI’s end, an overall … DOE Auspice Statement in any publications. And that can be found on our website as well. It’s also included in the …
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