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… about several different pieces of her work, including bacterial quorum sensing and its effects on regulation of … The genes are pretty much 100% identical. We don't know why one is expressed over the other. As far as whether we're … technology.] BETSY PARKINSON: OK. DNA affinity purification sequencing. And so the way this essentially works is you …

… FY 2026 DOE Metrics Sequencing Quarter Total Bases (Trillions) Operating Hours …     Q4 2026 175     2,208     *Includes Illumina and PacBio sequencing platforms. **Operating Hours target is based on … even though an individual may have several projects/roles. Sequencing Quarter Total Bases (Trillions) Operating Hours …

… The JGI has diverse capabilities in: DNA and RNA sequencing, Sample and library preparation, DNA synthesis … of standard analysis.  Raw data is provided for all sequencing products below. In addition, JGI will submit raw … have been  discontinued , including smRNA, bisulfite sequencing, and ChIP-seq. …

… other omics technologies.  The exponential growth of DNA sequencing data, coupled with recent computational … (Nature 2019). Other projects in the group include the sequencing and comparative analysis of thousands of archaeal and bacterial type strains ( GEBA-type strains project ), the …

… colleagues. Aaron is doing some cool stuff with cool bacteria that I’m fascinated to learn more about. He works … your interest in getting into natural products. DAN: Why are you here at SIMB? AARON PURI: Yeah. Thanks Jackie. … JGI and this was before they were integrated. So I thought, why not feed it in there. And I went to group meeting and …

… on synthetic biology of engineering gene expression in bacteria – however, the professor was actually quite … biological perspective, like what was this bacterium, and why did your group want to study it? Marnix Medema: You mean … gene clusters. And I had heard the first rumors of people sequencing like these enormous numbers of genomes, like 20 …

… the Broad that was looking to develop new methods for DNA sequencing of microbes. And what kept breaking our methods … functional was these secondary metabolite pathways. So why was that? What is it about secondary metabolite pathways … So, one of those is Acinetibacter . This is a genus of bacteria that’s really popped up at funding agencies and the …

… Bill Fenical. And we connected to JGI through the Community Sequencing Program, and they worked with us to sequence two … working with you, Dan, on this one, and we said, “Well, why don’t we have you know, the bioinformaticians go against … Initially, my group really focused on marine actinobacteria. Then we moved into marine proteobacteria. Not a …

… For sequencing or metabolomics projects: data are subject to a  … Sequencing and Metabolomics projects …

… in Nature and Medicine.” It’s obviously focused more on the bacterial side of the field, and it’s a little hard to find … and the 90s. And so we started to be able to explore DNA sequencing and actually get to the DNA sequence – sequences … Something that’s you know …  ALISON: Central! DAN: That’s why they called it that! But for, maybe, people who are less …

… is like, what’s your origin story in natural products? Why are you doing this? JACLYN WINTER: I’ll kind of go back … on identifying and characterizing haloperoxidases from bacteria. And with Christian, I started getting a little bit … to grow. If you hear Nigel talk, he is very interested in sequencing a lot more natural product-heavy culture …

… enzymes are, right? ALISON NARAYAN: Yes, and so that’s why I don’t like that sentence. I think that sometimes, we … [project] with JGI, how many flavin monooxygenases are you sequencing, sort of along that vein, of if you have one or … guess with along that line, with JGI, like how many are you sequencing currently? ALISON NARAYAN: Yeah. So– yeah, with …