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… of secondary metabolism.  DAN: Hello, and welcome back for Episode 7 of the Natural Prodcast. It’s been about a … them useful! DAN: Among many other things, Ben is maybe best known as an expert in enediynes – that’s a class of … other thing I think about JGI is, really, it’s probably the best place to do it. You have the sequencing capacity, you …

… genome miners use, including antiSMASH, MIBiG, and newer efforts, like BiG-scape and BiG-SLiCE, and now the BiG-FAM … it’s like when you write a book, the reader always knows best. So if all the readers are misinterpreting, you would … a nice example of going from a whole community with many microbes, hundreds of gene clusters, and then being able to …

… proposal call . This represents a unique opportunity for researchers to request the capabilities and expertise of … science, accelerating discoveries and developing transformative bio-based technologies that address challenges in … capabilities, they then ship samples—such as DNA and RNA for sequencing—to JGI. Users are responsible for covering …

… the series of interviews we recorded at the Society for Industrial Microbiology and Biotechnology (SIMB) Natural … looking to do is just find the natural enzymes with the best properties to then work with further. So for example, … allows us to ask the questions which ones express the best in E coli? Which ones are the most thermally stable? …

… to completion of standard analysis.  Raw data is provided for all sequencing products below. In addition, JGI will … to the  MassIVE repository . Not all products are available for all proposal calls.   Please review the call language … carefully to ensure that your request is appropriate for that call. Learn more about the  average base outputs …

… the Energy Sciences Network (ESnet) have been recognized for outstanding achievements in science, technology, and … Science user facilities. The HPCwire Editors Choice Award for Best Use of HPC in Life Sciences went to the Berkeley Lab … address some of the most pressing challenges of our time. For more information, please visit  …

… advanced sequencing technologies to decode the genomes of microbes in their natural environments. This work … diversity and metabolic potential, with implications for energy production, environmental sustainability, and many other applications. By understanding how microbes contribute to ecosystem functions, the Program …

… of single-cell genomes and directly link functional information with individual cells. Research Team    … sequence analysis to recover the genomes of uncultivated microbes. We also apply labeling strategies that allow us to select specific uncultivated microbes for sequencing based on their level of metabolic activity …

… (UEC) represents the JGI user community and is responsible for providing input and advice on JGI policies and practices … include: Make recommendations to the JGI regarding calls for proposals, including focus areas, eligibility, timing, … make recommendations on how the JGI Science Programs can best support the user community. Advise the JGI on other …

… Every approved proposal starts with a User Agreement — before any work can begin, including the submission of samples for sequencing, or the submission of sequencing data for synthesis. This agreement, required by the DOE for all … of the JGI User Agreement , JGI User Agreement for Federal Agencies , DNA Synthesis Appendix  and DNA …

… It’s been a while, but Natural Prodcast is back again for another round of episodes. If you stick around for the … on from JGI to do real journalism, and we wish her all the best. Later on, I’ll introduce my new co-host, who I’m … where smaller proposals may be a fit. Still not 20 many microbes. We still we work in plates, right? We’re a high …

… An assay used for profiling transcription factor binding sites across … samples in 96-well plates on automated liquid handler platforms, substantially increasing efficiency and scalability. … sequence analysis to recover the genomes of uncultivated microbes. We also apply labeling strategies that allow us to …