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Data Ecosystem
To expand access to integrated data, improve tools and … scales ranging from single genes and individual genomes to metagenomes to systems-level modeling and understanding. JGI …
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Natural Prodcast Episode 8: Eric Schmidt
… … DAN: You’re listening to the US Department of Energy Joint Genome … the end, we took an approach that was kind of a simplified metagenome sequencing approach to pick this system apart.  … of fantastic science, mainly in marine natural products structure elucidation, and he trained some of the greats in …
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Natural Prodcast Episode 19: Bill Fenical
… … DAN UDWARY: Hey, everyone. I’ve got a great episode for you here today. We got the … everybody else started looking at things and doing chemical structures, learning a little bit about things. And that was … is responsible for the division of the cell. You can see cartoons where you’ll have the chromosomes pulling apart …
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Natural Prodcast Episode 5: Brad Moore
… or a seaweed, were just having just remarkable chemical structures and things that people hadn’t seen. For every … environment you mentioned, you know that they can have consequences to marine life that surrounds it, whether it be … the end of last year. Dan: So these are going to be seaweed metagenomes? You’re sequencing everything? Brad: Metagenomes …
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The Surprising Structure of a Shrub Willow Sex Chromosome
A genetic architecture that is characteristic of the sex chromosomes of mammals is, for the first time, … been sequenced with sufficient resolution to analyze their structure. Scientists found both a gene likely important for … Palindromes are large inverted repeats with highly similar sequences so that their sequences read the same (or nearly) …
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Natural Prodcast Episode 17: Cassandra Quave
… that is often done, where we’re really just looking at DNA sequences, and we don’t always know necessarily or pay … there are now international regulations that provide a structure for ensuring that the countries that are the … to find new antibiotics and lifesaving treatments by seeking out healers and traditional medicines throughout the …
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Natural Prodcast Episode 16: Marcy Balunas
… … DAN: Hey Marcy!  ALISON: Hey Marcy?  MARCY: Hello. How’s it going?  DAN: Good. How are you?  MARCY: Am fine. I …
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Environmental Genomics Group
Research in the Eloe-Fadrosh group focuses on using genome-resolved metagenomic … computational approaches to sift through thousands of metagenomes for signatures of viruses and novel microbial … Clum, A. et al. (2021)  DOE JGI metagenome workflow …
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Protein structure determination using metagenome sequence data
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Mission
JGI Mission As a U.S. Department of Energy Office of Science user … earth, and environmental systems for energy and infrastructure security. The BER research program seeks to … basis of their behavior in the environment.  The JGI genome sequences and metabolomes of microbes and microbial …
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Natural Prodcast Episode 22: Alison Narayan
… … DAN UDWARY: Hey everyone. Welcome back to Natural Prodcast. This continues the … attraction to natural products was dual, the beauty of the structures and also the challenge and thinking about making … And so there are different ways that we decided which sequences made it onto that list. So the majority of them …
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Natural Prodcast Episode 24: Jackie Winter and SMC
Everything that we’re finding seems to be a new structure, and the microorganisms are novel. I mean, we have … the rest of the archaea and fungal genomes and then work on metagenomes. So yeah. So we’ve taken every public sequence … BGCs but highly fragmented, in most of the metagenome sequences that we’ve already analyzed. But that’s a whole …
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