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Natural Prodcast Episode 16: Marcy Balunas
… DAN: Hey Marcy!  ALISON: Hey Marcy?  MARCY: Hello. How’s it going?  DAN: Good. … easy to search for because there are patterns of domains, protein domains that you look for. And if you find those all … didn’t work as well. Why? There’s got to be some sort of protein or interaction or chemistry that the core-culture …
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Natural Prodcast Episode 23: Aaron Puri
… was jumping onto the I ntegrated Microbial Genomes and Metagenomes, the IMG platform that JGI has that really got … “tail of the acyl homoserine lactone” can have different structures, and that is akin to what you’re referring to … so far is that you can have very, very disparate amino acid sequences for synthases that produce the same signal. So …
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Micro-Scale Applications Group
… The Micro-Scale Applications group explores the genetic makeup of natural microbial communities … The JGI uniquely offers the first quantitative Stable Isotope Probing (SIP) Metagenomics pipeline that utilizes … The JGI provides users access to cutting-edge cell sorting, DNA …
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The Surprising Structure of a Shrub Willow Sex Chromosome
… A genetic architecture that is characteristic of the sex chromosomes of mammals is, for the first time, … been sequenced with sufficient resolution to analyze their structure. Scientists found both a gene likely important for … Palindromes are large inverted repeats with highly similar sequences so that their sequences read the same (or nearly) …
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How to Submit Sequencing Samples
… Below is a brief description of the process needed to prepare and ship samples for sequencing by … 1) Review JGI sample QC requirements and protocols Obtaining DNA and RNA of suitable quantity and quality … sends Project Manager (PM) a list of organism names (or for metagenomes, sample names).  Need help naming your …
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Viral Genomics Group
… Microbes drive critical ecosystem functions and affect global nutrient cycling, however they do so under strong … While an ever-increasing number of phage and virus genomes have been assembled and reported from metagenomes, our understanding of the impacts of these …
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Natural Prodcast Episode 4: Nancy Keller
… they’re complex, they have different tissues, different structures, different spores. I like looking at that I’m a … species”… he’s now found that some fungi have different ITS sequences in their genome, which might get you a little … Trying to even express a Cryptosporidium gene and get a protein product. It’s a very challenging organism to work …
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How To Use Our Systems
… One of the JGI’s key assets is our user community, comprising a broad range of researchers … spans tens of thousands of researchers. The JGI is always seeking to better understand our broader community of users. … Looking for BBTools? Find it here.  …
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Mining Metagenomes for Cas Proteins
… Cas14 proteins discovered from JGI’s IMG/M database and … Institute (JGI), a DOE Office of Science User Facility. The sequences were then biochemically characterized by a team … to foreign genetic elements by incorporating short sequences from infecting viruses and phages. In the event of …
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Natural Prodcast Episode 5: Brad Moore
… or a seaweed, were just having just remarkable chemical structures and things that people hadn’t seen. For every … environment you mentioned, you know that they can have consequences to marine life that surrounds it, whether it be … the end of last year. Dan: So these are going to be seaweed metagenomes? You’re sequencing everything? Brad: Metagenomes …
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Natural Prodcast Episode 17: Cassandra Quave
… that is often done, where we’re really just looking at DNA sequences, and we don’t always know necessarily or pay … there are now international regulations that provide a structure for ensuring that the countries that are the … screen to look at the interaction between SARS-coV-2 spike protein and the ACE2 receptor, so we’re looking at viral …
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Natural Prodcast Episode 13: Francisco Barona Goméz
… DAN UDWARY: You’re listening to the Department of Energy Joint Genome … that you need to do these coordination bonds, then many structures will be able to work. So, for example, in that … be the amino acid that is relevant for the synthesis of proteins, and will more often end up in the active site of …
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