Search

… some of the technical challenges to that, most of which seem to be history.   I should mention that this is one of … could do to us. So I’d say my initial entry was more, sort of, in an agricultural sense in that both on what … you know, how are our crops and people – in particular in developing countries – being affected by parasites.   NANCY: …

… the kinds of bacteria that, maybe, grow in one place and sort of stay there. And then, you know, they will have to … of plants. And these guys were sequenced, and you can see that different Frankia have different size genomes … often use primary metabolites as building blocks to produce novel molecules. And so we’ve got glycosides being made into …

… myself on my self-imposed schedule. So, we’ll have to see if I’m going to slip a day on releasing it into the … access the chemical potential of these or any organisms. So developing good heterologous expression hosts like maybe in … lot of sense to be spending a ton of energy producing some sort of– DAN: Especially as a system like a nonribosomal …

… Science Foundation to create international partnerships in developing countries for research into various aspects of … as part of the International Biodiversity Drug Discovery consortium doing natural products isolation/structure … the things I wanted from that experience was the chance to see what the industrial life was like. And I think I learned …

… CASSANDRA QUAVE: OK, great. Well, hey, it’s so great to see both of you, Dan and Alison. And I strangely feel like I … use successfully, hopefully, in the future even more so as novel therapies. And that’s how I got on that path of … materials that you’re working on or the products you’re developing are being worked on or accessed under the …

… you expose bacteria to your extract and hopefully, if you see the bacteria dying, then you know you’ve got an … lot of like synthetic chemistry effort to create a bunch of novel compounds that actually didn’t pan out. DAN: And there … but not as many as there were natural product hits. Sort of in parallel with that, the field of molecular …

… opportunity to talk more about some of the background and sort of the reasons why we want to do this. And also to … right. So I did a PhD in microbiology at MIT, and I studied microbial ecology. I studied Vibrio species in the ocean, so … molecules that they’re sharing and expressing, and that it seemed like we didn’t know very much about that world yet. …

…   Want to see past projects? Read more below         …

… I hope that doesn’t get me canceled.The monthly schedule seems to be working out, so expect lots more to come. Maybe … OK, so imagine this sentence comes across your desk. We’re developing this enzyme into a biocatalyst. Wasn’t it already … Or does it do a reaction selectively? DAN UDWARY: So it sort of does it work in the first place for instance? Is it …

… in natural products following him? I know a lot of people sort of veer off and go into different directions. Brad: … then they come home. The kid’s perspective. And you don’t see what happens behind that period of time. So for me, it … of, better understand fundamentally what’s going on in the cell as it responds to its ocean environment. And as we …

… Third parties (often referred to as “data users”) cannot see this data. Use-Restriction : A period in which data is … Read more about our publication policy and our efforts to see data produced by our facility result in scientific …